Subtypes based on cerebrospinal fluid and magnetic resonance imaging markers in normal elderly predict cognitive decline

Abstract Cerebrospinal fluid (CSF) and structural magnetic resonance imaging (MRI) show patterns of change in Alzheimer's disease (AD) that precede dementia. The Alzheimer's Disease Neuroimaging Initiative (ADNI) studied normal controls (NC), subjects with mild cognitive impairment (MCI),...

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Veröffentlicht in:	Neurobiology of aging 2010-08, Vol.31 (8), p.1419-1428
Hauptverfasser:	Nettiksimmons, J, Harvey, D, Brewer, J, Carmichael, O, DeCarli, C, Jack, C.R, Petersen, R, Shaw, L.M, Trojanowski, J.Q, Weiner, M.W, Beckett, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alzheimer Disease - cerebrospinal fluid Alzheimer Disease - classification Alzheimer Disease - pathology Alzheimer's disease Amyloid beta-protein Biomarkers - cerebrospinal fluid Cerebrospinal fluid Clustering Cognition Cognition Disorders - cerebrospinal fluid Cognition Disorders - classification Cognition Disorders - pathology Cross-Sectional Studies Dementia Early diagnosis Female Follow-Up Studies Hippocampal volume Humans Internal Medicine Longitudinal Studies Magnetic Resonance Imaging - methods Male Neurology Normal controls Predictive Value of Tests Prospective Studies Structural magnetic resonance imaging Tau protein
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