Crystal structure of human transglutaminase 2 in complex with adenosine triphosphate

Transglutaminase 2 (TG2) is a calcium-dependent multifunctional protein associated with various human diseases. We determined the crystal structure of human TG2 in complex with adenosine triphosphate (ATP). The ATP molecule binds to the previously identified guanosine diphosphate (GDP) binding pocke...

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Veröffentlicht in:	International journal of biological macromolecules 2010-08, Vol.47 (2), p.190-195
Hauptverfasser:	Han, Byeong-Gu, Cho, Jea-Won, Cho, Young Doo, Jeong, Kyung-Chae, Kim, Soo-Youl, Lee, Byung Il
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphate Adenosine Triphosphate - metabolism Amino Acid Sequence Animals ATP Binding Sites Crystal structure Crystallography, X-Ray Databases, Protein GTP-Binding Proteins - chemistry GTP-Binding Proteins - metabolism Guanosine Diphosphate - metabolism Humans Mice Models, Molecular Molecular Sequence Data Protein Conformation Transglutaminase 2 Transglutaminases - chemistry Transglutaminases - metabolism
Online-Zugang:	Volltext
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