Cell/tissue-tropic functions of Wnt5a signaling in normal and cancer cells

Correct spatio-temporal regulation of Wnt5a signaling is required for normal developmental morphogenesis, and defects in this pathway are linked to tumorigenesis. The precise role of Wnt5a signaling in cancer has, however, been a matter of controversy. Loss of Wnt5a signaling is related to developme...

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Veröffentlicht in:	Trends in cell biology 2010-06, Vol.20 (6), p.346-354
Hauptverfasser:	Nishita, Michiru, Enomoto, Masahiro, Yamagata, Kaoru, Minami, Yasuhiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line, Tumor Drosophila Humans Neoplasms - metabolism Pathology Proto-Oncogene Proteins - metabolism Receptor Tyrosine Kinase-like Orphan Receptors - metabolism Signal Transduction Wnt Proteins - metabolism Wnt-5a Protein
Online-Zugang:	Volltext
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