Proper differentiation of photoreceptors and amacrine cells depends on a regulatory loop between NeuroD and Six6

Timely generation of distinct neural cell types in appropriate numbers is fundamental for the generation of a functional retina. In vertebrates, the transcription factor Six6 is initially expressed in multipotent retina progenitors and then becomes restricted to differentiated retinal ganglion and a...

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Veröffentlicht in:Development (Cambridge) 2010-07, Vol.137 (14), p.2307-2317
Hauptverfasser: Conte, Ivan, Marco-Ferreres, Raquel, Beccari, Leonardo, Cisneros, Elsa, Ruiz, José María, Tabanera, Noemí, Bovolenta, Paola
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Sprache:eng
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