Effects of phlebotomy and phenylephrine infusion on portal venous pressure and systemic hemodynamics during liver transplantation

A regimen of fluid restriction, phlebotomy, vasopressors, and strict, protocol-guided product replacement has been associated with low blood product use during orthotopic liver transplantation. However, the physiologic basis of this strategy remains unclear. We hypothesized that a reduction of intra...

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Veröffentlicht in:	Transplantation 2010-04, Vol.89 (8), p.920-927
Hauptverfasser:	Massicotte, Luc, Perrault, Michel-Antoine, Denault, André Y, Klinck, John R, Beaulieu, Danielle, Roy, Jean-Denis, Thibeault, Lynda, Roy, André, McCormack, Michael, Karakiewicz, Pierre
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Loss, Surgical - prevention & control Cardiac Output - drug effects Catheterization, Swan-Ganz Central Venous Pressure - drug effects Echocardiography, Doppler, Color Echocardiography, Transesophageal Hemodynamics - drug effects Humans Infusions, Intravenous Liver Transplantation - adverse effects Liver Transplantation - methods Middle Aged Mitral Valve - diagnostic imaging Monitoring, Intraoperative - methods Phenylephrine - administration & dosage Phlebotomy Pilot Projects Portal Pressure - drug effects Pulmonary Wedge Pressure - drug effects Vascular Resistance - drug effects Vasoconstrictor Agents - administration & dosage
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