A call to arms: Using RNAi screening to improve oncolytic viral therapy

Abstract Replicating virus-based therapeutics for cancer, or oncolytic virus therapy (OVT), is rapidly emerging as a promising treatment modality for a wide range of cancers. In pre-clinical studies, oncolytic viruses have produced remarkable results in a variety of experimental animal models, and s...

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Veröffentlicht in:	Cytokine & growth factor reviews 2010-04, Vol.21 (2), p.161-167
Hauptverfasser:	Mahoney, D.J, Stojdl, D.F
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Animal models Animals Functional genomic screening Host-Pathogen Interactions Host/virus interaction Humans Oncolytic therapy Oncolytic Virotherapy - methods Oncolytic Viruses RNA Interference RNAi Virus Replication
Online-Zugang:	Volltext
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