Decreased initiation of DNA synthesis in a temperature-sensitive mutant of hamster cells

We have analyzed ongoing DNA replication in ts BN‐2, a dna− mutant of BHK‐21 cells (Nishimoto et al. '78). At the non‐permissive temperature of 39.5°C, inhibition of 3H‐thymidine into acid‐precipitable material begins 1 to 2 h after the cells are released from a block at the start of the S‐phas...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of cellular physiology 1980-11, Vol.105 (2), p.259-266
Hauptverfasser:	Eilen, Eric, Hand, Roger, Basilico, Claudio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Cricetinae DNA - biosynthesis Interphase Kidney Mutation Replicon Temperature
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!