Artifacts observed in critical-point-dried preparations of human chromosomes by electron microscopy
Preparations of eucaryotic chromosomes tend to suffer from the effects of moisture in critical-point drying and from mechanical stretching during preparation, resulting in fusion of fibers so that the latter are ultimately transformed into thick strands. Mechanical stretching alone is accompanied by...
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| Veröffentlicht in: | Journal of ultrastructure research 1980-10, Vol.73 (1), p.27-33 |
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| container_end_page | 33 |
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| container_title | Journal of ultrastructure research |
| container_volume | 73 |
| creator | Bahr, G.F. Engler, W.F. |
| description | Preparations of eucaryotic chromosomes tend to suffer from the effects of moisture in critical-point drying and from mechanical stretching during preparation, resulting in fusion of fibers so that the latter are ultimately transformed into thick strands. Mechanical stretching alone is accompanied by some fusion, but it may render insight into the architecture of chromosomes. |
| doi_str_mv | 10.1016/0022-5320(80)90113-6 |
| format | Article |
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Mechanical stretching alone is accompanied by some fusion, but it may render insight into the architecture of chromosomes.</description><identifier>ISSN: 0022-5320</identifier><identifier>EISSN: 1878-2345</identifier><identifier>DOI: 10.1016/0022-5320(80)90113-6</identifier><identifier>PMID: 7007660</identifier><language>eng</language><publisher>United States: Elsevier B.V</publisher><subject>Cells, Cultured ; Chromatin - ultrastructure ; Chromosomes, Human - ultrastructure ; Cytological Techniques ; Desiccation ; Humans ; Microscopy, Electron</subject><ispartof>Journal of ultrastructure research, 1980-10, Vol.73 (1), p.27-33</ispartof><rights>1980 Academic Press, Inc.</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-afee7c4aecd6ecca01ea36347961ac3842d26a3be67131d16b220402264622533</citedby><cites>FETCH-LOGICAL-c357t-afee7c4aecd6ecca01ea36347961ac3842d26a3be67131d16b220402264622533</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7007660$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bahr, G.F.</creatorcontrib><creatorcontrib>Engler, W.F.</creatorcontrib><title>Artifacts observed in critical-point-dried preparations of human chromosomes by electron microscopy</title><title>Journal of ultrastructure research</title><addtitle>J Ultrastruct Res</addtitle><description>Preparations of eucaryotic chromosomes tend to suffer from the effects of moisture in critical-point drying and from mechanical stretching during preparation, resulting in fusion of fibers so that the latter are ultimately transformed into thick strands. 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Mechanical stretching alone is accompanied by some fusion, but it may render insight into the architecture of chromosomes.</abstract><cop>United States</cop><pub>Elsevier B.V</pub><pmid>7007660</pmid><doi>10.1016/0022-5320(80)90113-6</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Journal of ultrastructure research, 1980-10, Vol.73 (1), p.27-33 |
| issn | 0022-5320 1878-2345 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_75425858 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Cells, Cultured Chromatin - ultrastructure Chromosomes, Human - ultrastructure Cytological Techniques Desiccation Humans Microscopy, Electron |
| title | Artifacts observed in critical-point-dried preparations of human chromosomes by electron microscopy |
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