The effect of pyrimethamine (daraprim) on the gametocytes and oocysts of Plasmodium falciparum and Plasmodium vivax

1. (1) Plasmodium vivax. When only 5 mg. or less of pyrimethamine was given, most of the oocysts developed normally and the resulting sporozoites were infective.Some, however, were drug-affected and failed to develop. When 50 mg. of pyrimethamine was given, none of the oocysts reached maturity even...

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Veröffentlicht in:	Transactions of the Royal Society of Tropical Medicine and Hygiene 1954, Vol.48 (1), p.50,IN1,53-52,IN2,63
Hauptverfasser:	Shute, P.G, Maryon, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antimalarials - pharmacology Humans Old Medline Oocysts Plasmodium falciparum - drug effects Plasmodium vivax - drug effects Pyrimethamine
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