Rapid Progression of Amyotrophic Lateral Sclerosis in an Acromegalic Patient After Surgical Resection of a Growth Hormone-Producing Pituitary Adenoma

INTRODUCTION:Insulin-like growth factor-1 (IGF-1) promotes the survival of neurons, mediates neuritic growth, and in 1 clinical trial human recombinant IGF-1 delayed the progression of functional impairment and decline of health-related quality of life in patients with amyotrophic lateral sclerosis...

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Veröffentlicht in:	The Neurologist (Baltimore, Md.) Md.), 2010-09, Vol.16 (5), p.315-318
Hauptverfasser:	Mondok, Agnes, Aranyi, Zsuzsanna, Kovacs, Gabor G., Czirjak, Sandor, Pusztai, Peter, Varga, Ibolya, Racz, Karoly
Format:	Artikel
Sprache:	eng
Schlagworte:	Acromegaly - drug therapy Acromegaly - physiopathology Acromegaly - surgery Aged Amyotrophic Lateral Sclerosis - etiology Amyotrophic Lateral Sclerosis - physiopathology Antineoplastic Agents, Hormonal - therapeutic use Disease Progression Fatal Outcome Female Growth Hormone-Secreting Pituitary Adenoma - complications Growth Hormone-Secreting Pituitary Adenoma - drug therapy Growth Hormone-Secreting Pituitary Adenoma - surgery Human Growth Hormone - deficiency Human Growth Hormone - therapeutic use Humans Insulin-Like Growth Factor I - metabolism Octreotide - therapeutic use Pituitary Neoplasms - complications Pituitary Neoplasms - drug therapy Pituitary Neoplasms - surgery
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