Treatment Delay and Excessive Substance Use in Bipolar Disorder
The aim of the present study was to investigate the relationship between treatment delay and excessive substance use. A total of 151 bipolar disorder (BD) I and II patients were consecutively recruited from in- and outpatient psychiatric units, and categorized as primary or secondary BD (without or...
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| Veröffentlicht in: | The journal of nervous and mental disease 2010-09, Vol.198 (9), p.628-633 |
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| container_title | The journal of nervous and mental disease |
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| creator | Lagerberg, Trine Vik Larsson, Sara Sundet, Kjetil Hansen, Charlotte B Hellvin, Tone Andreassen, Ole A Melle, Ingrid |
| description | The aim of the present study was to investigate the relationship between treatment delay and excessive substance use. A total of 151 bipolar disorder (BD) I and II patients were consecutively recruited from in- and outpatient psychiatric units, and categorized as primary or secondary BD (without or with antecedent excessive substance use). Predictors of treatment delay among all patients, and predictors of subsequent excessive substance use among primary BD patients, were investigated with logistic regression analyses. The median treatment delay was 2.0 years (IQR 14.0). The risk of long treatment delays was increased in patients with BD II disorder, no lifetime psychosis, a higher age at first contact with specialized psychiatric services, primary BD, and excessive substance use. In primary BD, the risk for developing excessive substance use was increased in males, in patients with shorter education and longer treatment delays. Patients with antecedent excessive substance use had reduced risk of long treatment delays. The risk of developing excessive substance use after BD onset increased with longer treatment delays. |
| doi_str_mv | 10.1097/NMD.0b013e3181ef3ef4 |
| format | Article |
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A total of 151 bipolar disorder (BD) I and II patients were consecutively recruited from in- and outpatient psychiatric units, and categorized as primary or secondary BD (without or with antecedent excessive substance use). Predictors of treatment delay among all patients, and predictors of subsequent excessive substance use among primary BD patients, were investigated with logistic regression analyses. The median treatment delay was 2.0 years (IQR 14.0). The risk of long treatment delays was increased in patients with BD II disorder, no lifetime psychosis, a higher age at first contact with specialized psychiatric services, primary BD, and excessive substance use. In primary BD, the risk for developing excessive substance use was increased in males, in patients with shorter education and longer treatment delays. Patients with antecedent excessive substance use had reduced risk of long treatment delays. 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Psychiatry ; Regression Analysis ; Risk Factors ; Severity of Illness Index ; Statistics, Nonparametric ; Studies ; Substance-Related Disorders - diagnosis ; Substance-Related Disorders - psychology ; Time Factors</subject><ispartof>The journal of nervous and mental disease, 2010-09, Vol.198 (9), p.628-633</ispartof><rights>2010 Lippincott Williams & Wilkins, Inc.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright Lippincott Williams & Wilkins Sep 2010</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4084-3dcc74b9ae39726f8a1a7f734c48bcde4a8e5135665b3743a6fe0aad9c31000a3</citedby><cites>FETCH-LOGICAL-c4084-3dcc74b9ae39726f8a1a7f734c48bcde4a8e5135665b3743a6fe0aad9c31000a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23284500$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20823723$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lagerberg, Trine Vik</creatorcontrib><creatorcontrib>Larsson, Sara</creatorcontrib><creatorcontrib>Sundet, Kjetil</creatorcontrib><creatorcontrib>Hansen, Charlotte B</creatorcontrib><creatorcontrib>Hellvin, Tone</creatorcontrib><creatorcontrib>Andreassen, Ole A</creatorcontrib><creatorcontrib>Melle, Ingrid</creatorcontrib><title>Treatment Delay and Excessive Substance Use in Bipolar Disorder</title><title>The journal of nervous and mental disease</title><addtitle>J Nerv Ment Dis</addtitle><description>The aim of the present study was to investigate the relationship between treatment delay and excessive substance use. A total of 151 bipolar disorder (BD) I and II patients were consecutively recruited from in- and outpatient psychiatric units, and categorized as primary or secondary BD (without or with antecedent excessive substance use). Predictors of treatment delay among all patients, and predictors of subsequent excessive substance use among primary BD patients, were investigated with logistic regression analyses. The median treatment delay was 2.0 years (IQR 14.0). The risk of long treatment delays was increased in patients with BD II disorder, no lifetime psychosis, a higher age at first contact with specialized psychiatric services, primary BD, and excessive substance use. In primary BD, the risk for developing excessive substance use was increased in males, in patients with shorter education and longer treatment delays. Patients with antecedent excessive substance use had reduced risk of long treatment delays. The risk of developing excessive substance use after BD onset increased with longer treatment delays.</description><subject>Addictive behaviors</subject><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Age Factors</subject><subject>Age of Onset</subject><subject>Biological and medical sciences</subject><subject>Bipolar disorder</subject><subject>Bipolar Disorder - psychology</subject><subject>Bipolar Disorder - therapy</subject><subject>Bipolar disorders</subject><subject>Clinical psychology</subject><subject>Diagnosis, Dual (Psychiatry)</subject><subject>Diagnostic and Statistical Manual of Mental Disorders</subject><subject>Drug use</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Mood disorders</subject><subject>Patients</subject><subject>Primary care</subject><subject>Psychiatry</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Regression Analysis</subject><subject>Risk Factors</subject><subject>Severity of Illness Index</subject><subject>Statistics, Nonparametric</subject><subject>Studies</subject><subject>Substance-Related Disorders - diagnosis</subject><subject>Substance-Related Disorders - psychology</subject><subject>Time Factors</subject><issn>0022-3018</issn><issn>1539-736X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkMFu1DAQhi1ERZfCGyAUISFOacceJ3ZOCLqFVipwoJW4WRNnoqZ4k8VOKH17XHWhUk_WWN_M_PMJ8UrCoYTGHH39sj6EFiQySiu5R-71E7GSFTalwfrHU7ECUKpEkHZfPE_pGkAa1PBM7CuwCo3ClXh_EZnmDY9zseZAtwWNXXHyx3NKw28uvi9tmmn0XFwmLoax-Dhsp0CxWA9pih3HF2Kvp5D45e49EJefTi6OT8vzb5_Pjj-cl16D1SV23hvdNsTYGFX3liSZPqfx2ra-Y02WK4lVXVctGo1U9wxEXeNRAgDhgXh3P3cbp18Lp9lthuQ5BBp5WpIzlQaFVkMm3zwir6cljjlchlRWkpVlSN9DPk4pRe7dNg4birdOgrvT67Je91hvbnu9m720G-7-N_3zmYG3O4CSp9DH7G5IDxwqqyuAh_03U5g5pp9hueHorpjCfOXyxVBBhWXOCtDkqrz70vgXpmGSIg</recordid><startdate>201009</startdate><enddate>201009</enddate><creator>Lagerberg, Trine Vik</creator><creator>Larsson, Sara</creator><creator>Sundet, Kjetil</creator><creator>Hansen, Charlotte B</creator><creator>Hellvin, Tone</creator><creator>Andreassen, Ole A</creator><creator>Melle, Ingrid</creator><general>Lippincott Williams & Wilkins, Inc</general><general>Lippincott Williams & Wilkins</general><general>Lippincott Williams & Wilkins Ovid Technologies</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201009</creationdate><title>Treatment Delay and Excessive Substance Use in Bipolar Disorder</title><author>Lagerberg, Trine Vik ; Larsson, Sara ; Sundet, Kjetil ; Hansen, Charlotte B ; Hellvin, Tone ; Andreassen, Ole A ; Melle, Ingrid</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4084-3dcc74b9ae39726f8a1a7f734c48bcde4a8e5135665b3743a6fe0aad9c31000a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Addictive behaviors</topic><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>Age Factors</topic><topic>Age of Onset</topic><topic>Biological and medical sciences</topic><topic>Bipolar disorder</topic><topic>Bipolar Disorder - psychology</topic><topic>Bipolar Disorder - therapy</topic><topic>Bipolar disorders</topic><topic>Clinical psychology</topic><topic>Diagnosis, Dual (Psychiatry)</topic><topic>Diagnostic and Statistical Manual of Mental Disorders</topic><topic>Drug use</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Mood disorders</topic><topic>Patients</topic><topic>Primary care</topic><topic>Psychiatry</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. 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| ispartof | The journal of nervous and mental disease, 2010-09, Vol.198 (9), p.628-633 |
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| subjects | Addictive behaviors Adult Adult and adolescent clinical studies Age Factors Age of Onset Biological and medical sciences Bipolar disorder Bipolar Disorder - psychology Bipolar Disorder - therapy Bipolar disorders Clinical psychology Diagnosis, Dual (Psychiatry) Diagnostic and Statistical Manual of Mental Disorders Drug use Female Humans Male Medical sciences Middle Aged Miscellaneous Mood disorders Patients Primary care Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Regression Analysis Risk Factors Severity of Illness Index Statistics, Nonparametric Studies Substance-Related Disorders - diagnosis Substance-Related Disorders - psychology Time Factors |
| title | Treatment Delay and Excessive Substance Use in Bipolar Disorder |
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