Effect of daily setup errors on individual dose distribution in conventional radiotherapy: an initial study
Recent linear accelerators can perform cone-beam computed tomography to correct setup errors immediately before dose delivery. We calculated the dose distribution with setup errors acquired from cone-beam computed tomography to determine a more realistic and individual effect of setup errors. The di...
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| Veröffentlicht in: | Radiological physics and technology 2009-07, Vol.2 (2), p.151-158 |
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| creator | Takemura, Akihiro Shoji, Saori Ueda, Sinichi Kurata, Yuichi Kumano, Tomoyasu Takamatsu, Shigeyuki Suzuki, Masayuki |
| description | Recent linear accelerators can perform cone-beam computed tomography to correct setup errors immediately before dose delivery. We calculated the dose distribution with setup errors acquired from cone-beam computed tomography to determine a more realistic and individual effect of setup errors. The differences in dose distribution were analyzed. The setup errors of three patients who were irradiated in the neck, esophagus, and pelvic area were obtained retrospectively. We found that the maximum dose variances for the three cases were 19.9–35.9%. The maximum dose variance points were relatively far from the isocenter. The volume of the 10% dose difference had widths of 1.3–1.85 cm around the beam edges. The V95 and mean doses at the clinical target volume were mostly unchanged. Doses around the beam edges were more varied than those around the isocenter for every case. The dose on the spinal cord located near the beam edges varied by 5–10% compared with the dose of the radiotherapy plan in two of the cases. We demonstrated the individual dose distributions of the cases affected by daily setup errors for all fractions. |
| doi_str_mv | 10.1007/s12194-009-0059-0 |
| format | Article |
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We calculated the dose distribution with setup errors acquired from cone-beam computed tomography to determine a more realistic and individual effect of setup errors. The differences in dose distribution were analyzed. The setup errors of three patients who were irradiated in the neck, esophagus, and pelvic area were obtained retrospectively. We found that the maximum dose variances for the three cases were 19.9–35.9%. The maximum dose variance points were relatively far from the isocenter. The volume of the 10% dose difference had widths of 1.3–1.85 cm around the beam edges. The V95 and mean doses at the clinical target volume were mostly unchanged. Doses around the beam edges were more varied than those around the isocenter for every case. The dose on the spinal cord located near the beam edges varied by 5–10% compared with the dose of the radiotherapy plan in two of the cases. 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We calculated the dose distribution with setup errors acquired from cone-beam computed tomography to determine a more realistic and individual effect of setup errors. The differences in dose distribution were analyzed. The setup errors of three patients who were irradiated in the neck, esophagus, and pelvic area were obtained retrospectively. We found that the maximum dose variances for the three cases were 19.9–35.9%. The maximum dose variance points were relatively far from the isocenter. The volume of the 10% dose difference had widths of 1.3–1.85 cm around the beam edges. The V95 and mean doses at the clinical target volume were mostly unchanged. Doses around the beam edges were more varied than those around the isocenter for every case. The dose on the spinal cord located near the beam edges varied by 5–10% compared with the dose of the radiotherapy plan in two of the cases. 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We calculated the dose distribution with setup errors acquired from cone-beam computed tomography to determine a more realistic and individual effect of setup errors. The differences in dose distribution were analyzed. The setup errors of three patients who were irradiated in the neck, esophagus, and pelvic area were obtained retrospectively. We found that the maximum dose variances for the three cases were 19.9–35.9%. The maximum dose variance points were relatively far from the isocenter. The volume of the 10% dose difference had widths of 1.3–1.85 cm around the beam edges. The V95 and mean doses at the clinical target volume were mostly unchanged. Doses around the beam edges were more varied than those around the isocenter for every case. The dose on the spinal cord located near the beam edges varied by 5–10% compared with the dose of the radiotherapy plan in two of the cases. 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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Aged Cone-Beam Computed Tomography Dose Fractionation Female Humans Imaging Imaging, Three-Dimensional Male Medical and Radiation Physics Medical Errors Medicine Medicine & Public Health Middle Aged Neoplasms - diagnostic imaging Neoplasms - radiotherapy Nuclear Medicine Radiology Radiotherapy Retrospective Studies Time Factors |
| title | Effect of daily setup errors on individual dose distribution in conventional radiotherapy: an initial study |
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