Simultaneous Determination of Piracetam and its Four Impurities by RP-HPLC with UV Detection

A simple and rapid high-performance liquid chromatographic method for the separation and determination of piracetam and its four impurities, 2-oxopyrrolidin-1-yl)acetic acid, pyrrolidin-2-one, methyl (2-oxopyrrolidin-1-yl)acetate, and ethyl (2-oxopyrrolidin-1-yl)acetate, was developed. The separatio...

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Veröffentlicht in:	Journal of chromatographic science 2010-08, Vol.48 (7), p.589-594
Hauptverfasser:	Arayne, M. Saeed, Sultana, Najma, Siddiqui, Farhan Ahmed, Mirza, Agha Zeeshan, Qureshi, Faiza, Zuberi, M. Hashim
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic Acid - analysis Acetic Acid - chemistry Analysis Biological and medical sciences Chromatography, High Pressure Liquid - methods Chromatography, Reverse-Phase - methods Drug Contamination Drug Stability General pharmacology Hydrogen-Ion Concentration Linear Models Medical sciences Pharmacology. Drug treatments Piracetam - analysis Piracetam - chemistry Pyrrolidinones - analysis Pyrrolidinones - chemistry Reproducibility of Results Spectrophotometry, Ultraviolet
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