Energy Delivery During 810 nm Endovenous Laser Ablation of Varicose Veins and Post-procedural Morbidity
Abstract Aim The durability of occlusion post endovenous laser therapy (EVLT) for varicose veins is linked to the magnitude of energy delivered to the vein and consequently increasing amounts of energy are employed. The aim of this study is to establish whether increasing the energy results in great...
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Veröffentlicht in: | European journal of vascular and endovascular surgery 2010-09, Vol.40 (3), p.393-398 |
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description | Abstract Aim The durability of occlusion post endovenous laser therapy (EVLT) for varicose veins is linked to the magnitude of energy delivered to the vein and consequently increasing amounts of energy are employed. The aim of this study is to establish whether increasing the energy results in greater periprocedural morbidity or complications. Methods Linear and logistic regression models were built to study the effect of energy delivery on outcome. The models controlled for age, gender, BMI, pre-operative quality of life and vein dimension. The outcomes were pain and analgesia requirement in week 1, change in disease specific quality of life (Aberdeen varicose vein questionnaire (AVVQ), change in generic quality of life (Short Form-36 (SF-36) and Euroqol (EQ5D)at week 1 and 6 and complication rates. The sample size calculation established that 115 patients would be required to detect any significant relationship. Results 232 patients were included. The mean (range) age was 50 (18–83) years. 63% were women. The mean (range) energy delivery was 89.8 (44.5–158.4) J/cm. There was no significant effect on any outcome related to increasing energy delivery. Conclusion Up to 160J/cm, increasing energy delivery has no significant effect upon the morbidity or complications of EVLT for superficial venous insufficiency. |
doi_str_mv | 10.1016/j.ejvs.2010.04.010 |
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The aim of this study is to establish whether increasing the energy results in greater periprocedural morbidity or complications. Methods Linear and logistic regression models were built to study the effect of energy delivery on outcome. The models controlled for age, gender, BMI, pre-operative quality of life and vein dimension. The outcomes were pain and analgesia requirement in week 1, change in disease specific quality of life (Aberdeen varicose vein questionnaire (AVVQ), change in generic quality of life (Short Form-36 (SF-36) and Euroqol (EQ5D)at week 1 and 6 and complication rates. The sample size calculation established that 115 patients would be required to detect any significant relationship. Results 232 patients were included. The mean (range) age was 50 (18–83) years. 63% were women. The mean (range) energy delivery was 89.8 (44.5–158.4) J/cm. There was no significant effect on any outcome related to increasing energy delivery. Conclusion Up to 160J/cm, increasing energy delivery has no significant effect upon the morbidity or complications of EVLT for superficial venous insufficiency.</description><identifier>ISSN: 1078-5884</identifier><identifier>EISSN: 1532-2165</identifier><identifier>DOI: 10.1016/j.ejvs.2010.04.010</identifier><identifier>PMID: 20510634</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Analgesics - therapeutic use ; Databases as Topic ; Endovenous laser ; Energy ; Female ; Humans ; Laser Therapy - adverse effects ; Laser Therapy - instrumentation ; Lasers - adverse effects ; Linear Models ; Logistic Models ; Male ; Middle Aged ; Odds Ratio ; Pain - drug therapy ; Pain - etiology ; Pain Measurement ; Quality of life ; Risk Assessment ; Risk Factors ; Surgery ; Time Factors ; Treatment Outcome ; Varicose veins ; Varicose Veins - surgery ; Venous Insufficiency - surgery ; Young Adult</subject><ispartof>European journal of vascular and endovascular surgery, 2010-09, Vol.40 (3), p.393-398</ispartof><rights>European Society for Vascular Surgery</rights><rights>2010 European Society for Vascular Surgery</rights><rights>Copyright 2010 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c454t-fa4b58e6402554a000914d23c2e23ed1280b143a9052678815b1743b46e95fa73</citedby><cites>FETCH-LOGICAL-c454t-fa4b58e6402554a000914d23c2e23ed1280b143a9052678815b1743b46e95fa73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.ejvs.2010.04.010$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20510634$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Carradice, D</creatorcontrib><creatorcontrib>Mazari, F.A.K</creatorcontrib><creatorcontrib>Mekako, A</creatorcontrib><creatorcontrib>Hatfield, J</creatorcontrib><creatorcontrib>Allgar, V</creatorcontrib><creatorcontrib>Chetter, I.C</creatorcontrib><title>Energy Delivery During 810 nm Endovenous Laser Ablation of Varicose Veins and Post-procedural Morbidity</title><title>European journal of vascular and endovascular surgery</title><addtitle>Eur J Vasc Endovasc Surg</addtitle><description>Abstract Aim The durability of occlusion post endovenous laser therapy (EVLT) for varicose veins is linked to the magnitude of energy delivered to the vein and consequently increasing amounts of energy are employed. The aim of this study is to establish whether increasing the energy results in greater periprocedural morbidity or complications. Methods Linear and logistic regression models were built to study the effect of energy delivery on outcome. The models controlled for age, gender, BMI, pre-operative quality of life and vein dimension. The outcomes were pain and analgesia requirement in week 1, change in disease specific quality of life (Aberdeen varicose vein questionnaire (AVVQ), change in generic quality of life (Short Form-36 (SF-36) and Euroqol (EQ5D)at week 1 and 6 and complication rates. The sample size calculation established that 115 patients would be required to detect any significant relationship. Results 232 patients were included. The mean (range) age was 50 (18–83) years. 63% were women. The mean (range) energy delivery was 89.8 (44.5–158.4) J/cm. There was no significant effect on any outcome related to increasing energy delivery. Conclusion Up to 160J/cm, increasing energy delivery has no significant effect upon the morbidity or complications of EVLT for superficial venous insufficiency.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Analgesics - therapeutic use</subject><subject>Databases as Topic</subject><subject>Endovenous laser</subject><subject>Energy</subject><subject>Female</subject><subject>Humans</subject><subject>Laser Therapy - adverse effects</subject><subject>Laser Therapy - instrumentation</subject><subject>Lasers - adverse effects</subject><subject>Linear Models</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Odds Ratio</subject><subject>Pain - drug therapy</subject><subject>Pain - etiology</subject><subject>Pain Measurement</subject><subject>Quality of life</subject><subject>Risk Assessment</subject><subject>Risk Factors</subject><subject>Surgery</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><subject>Varicose veins</subject><subject>Varicose Veins - surgery</subject><subject>Venous Insufficiency - surgery</subject><subject>Young Adult</subject><issn>1078-5884</issn><issn>1532-2165</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kc9u1DAQxi1ERUvbF-CAfOOUZfwvyUoIqSpbqLRVkWh7tRxnUhyydrGTlfZt-iw8GY627YEDvnwj6_tGM78h5B2DBQNWfuwX2G_TgkP-ALnI8oocMSV4wVmpXucaqrpQdS0PyduUegBQTKg35JDnAkohj8jPlcd4v6NfcHBbjLmYovP3tGbw59Fv6Mq3YYs-TImuTcJIz5rBjC54Gjp6Z6KzISG9Q-cTNb6l30Mai4cYLLZTNAO9CrFxrRt3J-SgM0PC0yc9JrcXq5vzb8X6-uvl-dm6sFLJseiMbFSNpQSulDR55CWTLReWIxfYMl5Dw6QwS1C8rOqaqYZVUjSyxKXqTCWOyYd93zzE7wnTqDcuWRwG4zFvoSslgeU3O_neaWNIKWKnH6LbmLjTDPQMWPd6BqxnwBqkzpJD75_aT80G25fIM9Fs-LQ3YF5y6zDqZB36zMNFtKNug_t__8__xO3gvLNm-IU7TH2Yos_4NNOJa9A_5hPPF2aZFC9LLv4Cz3agdQ</recordid><startdate>20100901</startdate><enddate>20100901</enddate><creator>Carradice, D</creator><creator>Mazari, F.A.K</creator><creator>Mekako, A</creator><creator>Hatfield, J</creator><creator>Allgar, V</creator><creator>Chetter, I.C</creator><general>Elsevier Ltd</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20100901</creationdate><title>Energy Delivery During 810 nm Endovenous Laser Ablation of Varicose Veins and Post-procedural Morbidity</title><author>Carradice, D ; Mazari, F.A.K ; Mekako, A ; Hatfield, J ; Allgar, V ; Chetter, I.C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c454t-fa4b58e6402554a000914d23c2e23ed1280b143a9052678815b1743b46e95fa73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Analgesics - therapeutic use</topic><topic>Databases as Topic</topic><topic>Endovenous laser</topic><topic>Energy</topic><topic>Female</topic><topic>Humans</topic><topic>Laser Therapy - adverse effects</topic><topic>Laser Therapy - instrumentation</topic><topic>Lasers - adverse effects</topic><topic>Linear Models</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Odds Ratio</topic><topic>Pain - drug therapy</topic><topic>Pain - etiology</topic><topic>Pain Measurement</topic><topic>Quality of life</topic><topic>Risk Assessment</topic><topic>Risk Factors</topic><topic>Surgery</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><topic>Varicose veins</topic><topic>Varicose Veins - surgery</topic><topic>Venous Insufficiency - surgery</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Carradice, D</creatorcontrib><creatorcontrib>Mazari, F.A.K</creatorcontrib><creatorcontrib>Mekako, A</creatorcontrib><creatorcontrib>Hatfield, J</creatorcontrib><creatorcontrib>Allgar, V</creatorcontrib><creatorcontrib>Chetter, I.C</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of vascular and endovascular surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Carradice, D</au><au>Mazari, F.A.K</au><au>Mekako, A</au><au>Hatfield, J</au><au>Allgar, V</au><au>Chetter, I.C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Energy Delivery During 810 nm Endovenous Laser Ablation of Varicose Veins and Post-procedural Morbidity</atitle><jtitle>European journal of vascular and endovascular surgery</jtitle><addtitle>Eur J Vasc Endovasc Surg</addtitle><date>2010-09-01</date><risdate>2010</risdate><volume>40</volume><issue>3</issue><spage>393</spage><epage>398</epage><pages>393-398</pages><issn>1078-5884</issn><eissn>1532-2165</eissn><abstract>Abstract Aim The durability of occlusion post endovenous laser therapy (EVLT) for varicose veins is linked to the magnitude of energy delivered to the vein and consequently increasing amounts of energy are employed. The aim of this study is to establish whether increasing the energy results in greater periprocedural morbidity or complications. Methods Linear and logistic regression models were built to study the effect of energy delivery on outcome. The models controlled for age, gender, BMI, pre-operative quality of life and vein dimension. The outcomes were pain and analgesia requirement in week 1, change in disease specific quality of life (Aberdeen varicose vein questionnaire (AVVQ), change in generic quality of life (Short Form-36 (SF-36) and Euroqol (EQ5D)at week 1 and 6 and complication rates. The sample size calculation established that 115 patients would be required to detect any significant relationship. Results 232 patients were included. The mean (range) age was 50 (18–83) years. 63% were women. The mean (range) energy delivery was 89.8 (44.5–158.4) J/cm. There was no significant effect on any outcome related to increasing energy delivery. Conclusion Up to 160J/cm, increasing energy delivery has no significant effect upon the morbidity or complications of EVLT for superficial venous insufficiency.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>20510634</pmid><doi>10.1016/j.ejvs.2010.04.010</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adolescent Adult Aged Aged, 80 and over Analgesics - therapeutic use Databases as Topic Endovenous laser Energy Female Humans Laser Therapy - adverse effects Laser Therapy - instrumentation Lasers - adverse effects Linear Models Logistic Models Male Middle Aged Odds Ratio Pain - drug therapy Pain - etiology Pain Measurement Quality of life Risk Assessment Risk Factors Surgery Time Factors Treatment Outcome Varicose veins Varicose Veins - surgery Venous Insufficiency - surgery Young Adult |
title | Energy Delivery During 810 nm Endovenous Laser Ablation of Varicose Veins and Post-procedural Morbidity |
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