Pseudo tumoral gastric amyloidosis: a case report

Amyloidosis is an abnormal extracellular deposition of insoluble proteins, which is associated with an involvement of the gastrointestinal tract in 50 to 70% of cases. In primary amyloïdosis (light chain amyloïdosis), localized gastric involvement is a rare finding which can mimick malignancy. To el...

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Veröffentlicht in:Tunisie Medicale 2010-09, Vol.88 (9), p.670-673
Hauptverfasser: Nfoussi, Haifa, Chelly, Ines, Bellil, Khadija, Kchir, Nidhameddine, Haouet, Slim, Zitouna, Moncef
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container_issue 9
container_start_page 670
container_title Tunisie Medicale
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creator Nfoussi, Haifa
Chelly, Ines
Bellil, Khadija
Kchir, Nidhameddine
Haouet, Slim
Zitouna, Moncef
description Amyloidosis is an abnormal extracellular deposition of insoluble proteins, which is associated with an involvement of the gastrointestinal tract in 50 to 70% of cases. In primary amyloïdosis (light chain amyloïdosis), localized gastric involvement is a rare finding which can mimick malignancy. To elucidate the clinical, histological and therapeutic features of pseudo tumoral gastric amyloidosis via a rare report along with a review of related literatures. We report the case of a 56-year-old man, admitted with upper digestive outlet obstruction. Linitis plastica with lymph node involvement was suspected by gastroscopy, barium meal and endoscopic ultrasonography but was not confirmed by gastric biopsies. The patient was treated with total gastrectomy with lymph node dissection. Pathological examination demonstrated gastric and lymph nodes amyloidosis and no malignant tumor was found. We propose that amyloidosis should be considered in the differential diagnosis of gastric tumors.
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection
subjects Amyloidosis - diagnosis
Amyloidosis - surgery
Diagnosis, Differential
Gastric Outlet Obstruction - etiology
Gastric Outlet Obstruction - surgery
Humans
Lymphatic Diseases - diagnosis
Lymphatic Diseases - surgery
Male
Middle Aged
Stomach Diseases - diagnosis
Stomach Diseases - surgery
Stomach Neoplasms - diagnosis
title Pseudo tumoral gastric amyloidosis: a case report
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