Pseudo tumoral gastric amyloidosis: a case report
Amyloidosis is an abnormal extracellular deposition of insoluble proteins, which is associated with an involvement of the gastrointestinal tract in 50 to 70% of cases. In primary amyloïdosis (light chain amyloïdosis), localized gastric involvement is a rare finding which can mimick malignancy. To el...
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Veröffentlicht in: | Tunisie Medicale 2010-09, Vol.88 (9), p.670-673 |
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creator | Nfoussi, Haifa Chelly, Ines Bellil, Khadija Kchir, Nidhameddine Haouet, Slim Zitouna, Moncef |
description | Amyloidosis is an abnormal extracellular deposition of insoluble proteins, which is associated with an involvement of the gastrointestinal tract in 50 to 70% of cases. In primary amyloïdosis (light chain amyloïdosis), localized gastric involvement is a rare finding which can mimick malignancy.
To elucidate the clinical, histological and therapeutic features of pseudo tumoral gastric amyloidosis via a rare report along with a review of related literatures.
We report the case of a 56-year-old man, admitted with upper digestive outlet obstruction. Linitis plastica with lymph node involvement was suspected by gastroscopy, barium meal and endoscopic ultrasonography but was not confirmed by gastric biopsies. The patient was treated with total gastrectomy with lymph node dissection. Pathological examination demonstrated gastric and lymph nodes amyloidosis and no malignant tumor was found.
We propose that amyloidosis should be considered in the differential diagnosis of gastric tumors. |
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To elucidate the clinical, histological and therapeutic features of pseudo tumoral gastric amyloidosis via a rare report along with a review of related literatures.
We report the case of a 56-year-old man, admitted with upper digestive outlet obstruction. Linitis plastica with lymph node involvement was suspected by gastroscopy, barium meal and endoscopic ultrasonography but was not confirmed by gastric biopsies. The patient was treated with total gastrectomy with lymph node dissection. Pathological examination demonstrated gastric and lymph nodes amyloidosis and no malignant tumor was found.
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To elucidate the clinical, histological and therapeutic features of pseudo tumoral gastric amyloidosis via a rare report along with a review of related literatures.
We report the case of a 56-year-old man, admitted with upper digestive outlet obstruction. Linitis plastica with lymph node involvement was suspected by gastroscopy, barium meal and endoscopic ultrasonography but was not confirmed by gastric biopsies. The patient was treated with total gastrectomy with lymph node dissection. Pathological examination demonstrated gastric and lymph nodes amyloidosis and no malignant tumor was found.
We propose that amyloidosis should be considered in the differential diagnosis of gastric tumors.</description><subject>Amyloidosis - diagnosis</subject><subject>Amyloidosis - surgery</subject><subject>Diagnosis, Differential</subject><subject>Gastric Outlet Obstruction - etiology</subject><subject>Gastric Outlet Obstruction - surgery</subject><subject>Humans</subject><subject>Lymphatic Diseases - diagnosis</subject><subject>Lymphatic Diseases - surgery</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Stomach Diseases - diagnosis</subject><subject>Stomach Diseases - surgery</subject><subject>Stomach Neoplasms - diagnosis</subject><issn>0041-4131</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1jztrwzAURjW0NCHNXyjaOhl09YrSrYS-INAO2c2VdF1c5MqV7CH_voam3_IthwPniq2F0NBoULBi21q_xDIrYG_ghq2kcCDBqTWDj0pzzHyah1ww8U-sU-kDx-Gcch9z7esDRx6wEi805jLdsusOU6Xt5Tfs9Px0Orw2x_eXt8PjsRmNUU0HVu6Vk94DRQrB26i8dcJaUuQ6452NO5RoZTAYQSwACiQI2oagpVYbdv-nHUv-malO7dDXQCnhN-W5tjujlyAn1ELeXcjZDxTbsfQDlnP7H6l-AevkTRY</recordid><startdate>201009</startdate><enddate>201009</enddate><creator>Nfoussi, Haifa</creator><creator>Chelly, Ines</creator><creator>Bellil, Khadija</creator><creator>Kchir, Nidhameddine</creator><creator>Haouet, Slim</creator><creator>Zitouna, Moncef</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201009</creationdate><title>Pseudo tumoral gastric amyloidosis: a case report</title><author>Nfoussi, Haifa ; Chelly, Ines ; Bellil, Khadija ; Kchir, Nidhameddine ; Haouet, Slim ; Zitouna, Moncef</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p553-f1629382bb1edeccb6d3b68066e3e8f5b86d7a2a62c5ad10cb6a0ae1c46cc4243</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>fre</language><creationdate>2010</creationdate><topic>Amyloidosis - diagnosis</topic><topic>Amyloidosis - surgery</topic><topic>Diagnosis, Differential</topic><topic>Gastric Outlet Obstruction - etiology</topic><topic>Gastric Outlet Obstruction - surgery</topic><topic>Humans</topic><topic>Lymphatic Diseases - diagnosis</topic><topic>Lymphatic Diseases - surgery</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Stomach Diseases - diagnosis</topic><topic>Stomach Diseases - surgery</topic><topic>Stomach Neoplasms - diagnosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nfoussi, Haifa</creatorcontrib><creatorcontrib>Chelly, Ines</creatorcontrib><creatorcontrib>Bellil, Khadija</creatorcontrib><creatorcontrib>Kchir, Nidhameddine</creatorcontrib><creatorcontrib>Haouet, Slim</creatorcontrib><creatorcontrib>Zitouna, Moncef</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Tunisie Medicale</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nfoussi, Haifa</au><au>Chelly, Ines</au><au>Bellil, Khadija</au><au>Kchir, Nidhameddine</au><au>Haouet, Slim</au><au>Zitouna, Moncef</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pseudo tumoral gastric amyloidosis: a case report</atitle><jtitle>Tunisie Medicale</jtitle><addtitle>Tunis Med</addtitle><date>2010-09</date><risdate>2010</risdate><volume>88</volume><issue>9</issue><spage>670</spage><epage>673</epage><pages>670-673</pages><issn>0041-4131</issn><abstract>Amyloidosis is an abnormal extracellular deposition of insoluble proteins, which is associated with an involvement of the gastrointestinal tract in 50 to 70% of cases. In primary amyloïdosis (light chain amyloïdosis), localized gastric involvement is a rare finding which can mimick malignancy.
To elucidate the clinical, histological and therapeutic features of pseudo tumoral gastric amyloidosis via a rare report along with a review of related literatures.
We report the case of a 56-year-old man, admitted with upper digestive outlet obstruction. Linitis plastica with lymph node involvement was suspected by gastroscopy, barium meal and endoscopic ultrasonography but was not confirmed by gastric biopsies. The patient was treated with total gastrectomy with lymph node dissection. Pathological examination demonstrated gastric and lymph nodes amyloidosis and no malignant tumor was found.
We propose that amyloidosis should be considered in the differential diagnosis of gastric tumors.</abstract><cop>Tunisia</cop><pmid>20812183</pmid><tpages>4</tpages></addata></record> |
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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
subjects | Amyloidosis - diagnosis Amyloidosis - surgery Diagnosis, Differential Gastric Outlet Obstruction - etiology Gastric Outlet Obstruction - surgery Humans Lymphatic Diseases - diagnosis Lymphatic Diseases - surgery Male Middle Aged Stomach Diseases - diagnosis Stomach Diseases - surgery Stomach Neoplasms - diagnosis |
title | Pseudo tumoral gastric amyloidosis: a case report |
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