Recent data about the role of human papillomavirus (HPV) in oncogenesis of head and neck cancer
Human papillomavirus (HPV) is a small circular DNA-virus and the high-risk types 16, 18 is implicated in oncogenesis of head and neck cancer--especially oropharynx (tonsil and base of tongue), poorly differentiated (the basaloid type), locoregional advanced stage, poorly differentiated, at the young...
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| Veröffentlicht in: | Romanian journal of morphology and embryology 2010, Vol.51 (3), p.437-440 |
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| container_title | Romanian journal of morphology and embryology |
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| creator | Bădulescu, Fl Crişan, Anda Bădulescu, Adriana Schenker, M |
| description | Human papillomavirus (HPV) is a small circular DNA-virus and the high-risk types 16, 18 is implicated in oncogenesis of head and neck cancer--especially oropharynx (tonsil and base of tongue), poorly differentiated (the basaloid type), locoregional advanced stage, poorly differentiated, at the younger male, non-smokers, non-drinkers, sexual behaviors. The prognostic is favorable of human papillomavirus tumor status for patients with oropharynx squamous cell carcinoma treated with radiotherapy (accelerated fractionation without total dose reduction). The impact of HPV-vaccination (ACIP 2007) decreasing the incidence of oropharyngeal cancer, but that patients HPV-positive, have good prognostic in generally (two-year overall survival: 95%, two-year progression-free survival: 88%), therefore HPV-vaccination in routine practice it is controversy. |
| format | Article |
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| ispartof | Romanian journal of morphology and embryology, 2010, Vol.51 (3), p.437-440 |
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| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Clinical Trials as Topic Head and Neck Neoplasms - etiology Head and Neck Neoplasms - pathology Head and Neck Neoplasms - therapy Head and Neck Neoplasms - virology Humans Male Papillomaviridae - physiology Precancerous Conditions - pathology Precancerous Conditions - virology |
| title | Recent data about the role of human papillomavirus (HPV) in oncogenesis of head and neck cancer |
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