Perioperative platelet and monocyte activation in patients with critical limb ischemia

Background Patients with critical limb ischemia (CLI) have a high rate of adverse cardiovascular events, particularly when undergoing surgery. We sought to determine the effect of surgery and vascular disease on platelet and monocyte activation in vivo in patients with CLI. Methods An observational,...

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Veröffentlicht in:	Journal of vascular surgery 2010-09, Vol.52 (3), p.697-703
Hauptverfasser:	Burdess, Anne, MBChB, Nimmo, Alastair F., MBChB, Campbell, Neil, BMedSci, Harding, Scott A., MBChB, MD, Garden, O.J., MBChB, MD, Dawson, A. Raymond, MBChB, MD, Newby, David E., MBChB, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anesthesia Anesthesia depending on type of surgery Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Biomarkers - blood Blood Platelets - metabolism CD11b Antigen - blood CD40 Antigens - blood Cell-Derived Microparticles - metabolism Chi-Square Distribution Critical Illness Cross-Sectional Studies Female Flow Cytometry Humans Ischemia - blood Ischemia - surgery Lower Extremity - blood supply Male Medical sciences Middle Aged Monocytes - metabolism P-Selectin - blood Platelet Activation Platelet Aggregation Inhibitors - therapeutic use Scotland Surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Thoracic and cardiovascular surgery. Cardiopulmonary bypass Vascular surgery: aorta, extremities, vena cava. Surgery of the lymphatic vessels Vascular Surgical Procedures - adverse effects
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