Blood pyruvate carboxylase activity as a criterion of biotin status in young pigs
A basal diet containing isolated soybean protein was supplemented with 100 and 500 μg biotin/kg and another basal diet containing hen-egg albumen was supplemented with 1300 μg biotin/kg. The five diets were fed to groups of young pigs from four to 12 weeks old. Growth depression or skin or foot lesi...
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Veröffentlicht in: | Research in veterinary science 1980-07, Vol.29 (1), p.126-128 |
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creator | Whitehead, C.C. Bannister, D.W. D’Mello, J.P.F. |
description | A basal diet containing isolated soybean protein was supplemented with 100 and 500 μg biotin/kg and another basal diet containing hen-egg albumen was supplemented with 1300 μg biotin/kg. The five diets were fed to groups of young pigs from four to 12 weeks old. Growth depression or skin or foot lesions characteristic of biotin deficiency were not seen but the undersurfaces of the hooves of pigs given the basal albumen diet were unusually soft. Blood pyruvate carboxylase activity showed a maximum response to dietary biotin at six weeks but by 12 weeks there was no response to supplemental levels greater than 100 μg/kg. Plasma biotin concentration gave a good indication of biotin intake at all ages. |
doi_str_mv | 10.1016/S0034-5288(18)32704-8 |
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The five diets were fed to groups of young pigs from four to 12 weeks old. Growth depression or skin or foot lesions characteristic of biotin deficiency were not seen but the undersurfaces of the hooves of pigs given the basal albumen diet were unusually soft. Blood pyruvate carboxylase activity showed a maximum response to dietary biotin at six weeks but by 12 weeks there was no response to supplemental levels greater than 100 μg/kg. 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The five diets were fed to groups of young pigs from four to 12 weeks old. Growth depression or skin or foot lesions characteristic of biotin deficiency were not seen but the undersurfaces of the hooves of pigs given the basal albumen diet were unusually soft. Blood pyruvate carboxylase activity showed a maximum response to dietary biotin at six weeks but by 12 weeks there was no response to supplemental levels greater than 100 μg/kg. Plasma biotin concentration gave a good indication of biotin intake at all ages.</description><subject>Administration, Oral</subject><subject>Animals</subject><subject>Biotin - administration & dosage</subject><subject>Biotin - blood</subject><subject>Diet</subject><subject>Pyruvate Carboxylase - blood</subject><subject>Swine - blood</subject><issn>0034-5288</issn><issn>1532-2661</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1980</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLAzEUhYMotT5-gpCV6GI0aV4zK9HiCwQR3Yckc6dEppOaZIrz7x3b4tbVvXDOuY8PoTNKriih8vqdEMYLMSvLC1pespkivCj30JQKNitmUtJ9NP2zHKKjlD4JIZxSNUETxYVgXE7R210bQo1XQ-zXJgN2JtrwPbQmATYu-7XPAzYJG-yizxB96HBosPUh-w6nbHKf8NgNoe8WeOUX6QQdNKZNcLqrx-jj4f5j_lS8vD4-z29fCsckyYW1wgnbEAWlrYQCyyW3TDVKMWesGs_koChXlElVlZVtjLRG1aoynBri2DE6345dxfDVQ8p66ZODtjUdhD5pJVglCSejUWyNLoaUIjR6Ff3SxEFTon9J6g1J_YtJ01JvSOpyzJ3tFvR2CfVfaodu1G-2OoxPrj1EnZyHzkHtI7is6-D_2fADegODlg</recordid><startdate>198007</startdate><enddate>198007</enddate><creator>Whitehead, C.C.</creator><creator>Bannister, D.W.</creator><creator>D’Mello, J.P.F.</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198007</creationdate><title>Blood pyruvate carboxylase activity as a criterion of biotin status in young pigs</title><author>Whitehead, C.C. ; Bannister, D.W. ; D’Mello, J.P.F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c360t-bb5c5bf07e8b957eb464b37f773cab71174e71471367989bfa6ba7d79a41a0c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1980</creationdate><topic>Administration, Oral</topic><topic>Animals</topic><topic>Biotin - administration & dosage</topic><topic>Biotin - blood</topic><topic>Diet</topic><topic>Pyruvate Carboxylase - blood</topic><topic>Swine - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Whitehead, C.C.</creatorcontrib><creatorcontrib>Bannister, D.W.</creatorcontrib><creatorcontrib>D’Mello, J.P.F.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Research in veterinary science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Whitehead, C.C.</au><au>Bannister, D.W.</au><au>D’Mello, J.P.F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Blood pyruvate carboxylase activity as a criterion of biotin status in young pigs</atitle><jtitle>Research in veterinary science</jtitle><addtitle>Res Vet Sci</addtitle><date>1980-07</date><risdate>1980</risdate><volume>29</volume><issue>1</issue><spage>126</spage><epage>128</epage><pages>126-128</pages><issn>0034-5288</issn><eissn>1532-2661</eissn><abstract>A basal diet containing isolated soybean protein was supplemented with 100 and 500 μg biotin/kg and another basal diet containing hen-egg albumen was supplemented with 1300 μg biotin/kg. The five diets were fed to groups of young pigs from four to 12 weeks old. Growth depression or skin or foot lesions characteristic of biotin deficiency were not seen but the undersurfaces of the hooves of pigs given the basal albumen diet were unusually soft. Blood pyruvate carboxylase activity showed a maximum response to dietary biotin at six weeks but by 12 weeks there was no response to supplemental levels greater than 100 μg/kg. Plasma biotin concentration gave a good indication of biotin intake at all ages.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>7455346</pmid><doi>10.1016/S0034-5288(18)32704-8</doi><tpages>3</tpages></addata></record> |
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subjects | Administration, Oral Animals Biotin - administration & dosage Biotin - blood Diet Pyruvate Carboxylase - blood Swine - blood |
title | Blood pyruvate carboxylase activity as a criterion of biotin status in young pigs |
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