Large-cell calcifying Sertoli cell tumor of the testis
Ten cases of a distinctive testicular neoplasm characterized by large cells with abundant eosinophilic cytoplasm and calcification are reported together with two similar cases from the literature. A Sertoli cell origin of these tumors was established by their architectural and cytologic characterist...
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Veröffentlicht in: | American journal of clinical pathology 1980-11, Vol.74 (5), p.607-619 |
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creator | Proppe, K H Scully, R E |
description | Ten cases of a distinctive testicular neoplasm characterized by large cells with abundant eosinophilic cytoplasm and calcification are reported together with two similar cases from the literature. A Sertoli cell origin of these tumors was established by their architectural and cytologic characteristics, as well as their frequent growth within seminiferous tubules. A high association was found with unusual features, including bilaterality (six cases), multifocality (six cases), complex endocrine disorders, (three cases), and familial occurrence and cardiac myxoma (two cases). Eleven of the 12 cases had benign courses, but one was associated with metastases that caused death. |
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A Sertoli cell origin of these tumors was established by their architectural and cytologic characteristics, as well as their frequent growth within seminiferous tubules. A high association was found with unusual features, including bilaterality (six cases), multifocality (six cases), complex endocrine disorders, (three cases), and familial occurrence and cardiac myxoma (two cases). 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issn | 0002-9173 1943-7722 |
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source | Oxford University Press Journals Digital Archive legacy; MEDLINE |
subjects | Adolescent Adult Calcinosis - pathology Child Child, Preschool Female Humans Male Microscopy, Electron Sertoli Cell Tumor - pathology Testicular Neoplasms - pathology |
title | Large-cell calcifying Sertoli cell tumor of the testis |
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