Anaplastic thyroid carcinoma: Long-term survival after radical surgery
Anaplastic carcinoma of the thyroid is a highly malignant disease with few survivors over one year. Radical surgery and laryngectomy are usually considered contraindicated. A 50‐year‐old woman with a history of papillary carcinoma treated with external radiation developed anaplastic giant‐cell carci...
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Veröffentlicht in: | Journal of surgical oncology 1980-01, Vol.14 (4), p.389-394 |
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container_title | Journal of surgical oncology |
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creator | Goldman, Joel M. Goren, Elihu N. Cohen, Max H. Webber, Bruce L. Brennan, Murray F. Robbins, Jacob |
description | Anaplastic carcinoma of the thyroid is a highly malignant disease with few survivors over one year. Radical surgery and laryngectomy are usually considered contraindicated. A 50‐year‐old woman with a history of papillary carcinoma treated with external radiation developed anaplastic giant‐cell carcinoma of the thyroid invading the soft tissues of the neck including the larynx. Since surgery was felt to represent her only chance for survival, she underwent laryngopharyngectomy, right radical‐neck dissection, and pharyngeal reconstruction. Three years after the surgery was performed, she is living an active life with only minor handicaps. Nevertheless, multiple nodules were noted in her lungs on recent tomographic examination. Our experience with this woman suggests that there is a role for radical surgery and laryngectomy in selected cases of anaplastic carcinoma. |
doi_str_mv | 10.1002/jso.2930140413 |
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Radical surgery and laryngectomy are usually considered contraindicated. A 50‐year‐old woman with a history of papillary carcinoma treated with external radiation developed anaplastic giant‐cell carcinoma of the thyroid invading the soft tissues of the neck including the larynx. Since surgery was felt to represent her only chance for survival, she underwent laryngopharyngectomy, right radical‐neck dissection, and pharyngeal reconstruction. Three years after the surgery was performed, she is living an active life with only minor handicaps. Nevertheless, multiple nodules were noted in her lungs on recent tomographic examination. Our experience with this woman suggests that there is a role for radical surgery and laryngectomy in selected cases of anaplastic carcinoma.</description><identifier>ISSN: 0022-4790</identifier><identifier>EISSN: 1096-9098</identifier><identifier>DOI: 10.1002/jso.2930140413</identifier><identifier>PMID: 7442263</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>anaplastic carcinoma ; Carcinoma - etiology ; Carcinoma - surgery ; Carcinoma, Papillary - complications ; Female ; Humans ; Laryngectomy ; laryngopharyngectomy ; Middle Aged ; Neck Dissection ; Pharyngectomy ; Prognosis ; thyroid ; Thyroid Neoplasms - etiology ; Thyroid Neoplasms - surgery</subject><ispartof>Journal of surgical oncology, 1980-01, Vol.14 (4), p.389-394</ispartof><rights>Copyright © 1980 Wiley‐Liss, Inc., A Wiley Company</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3783-8952b8f2f624149239ee53cac5145b79bec5f862fde79ddb48c056480fb4a76e3</citedby><cites>FETCH-LOGICAL-c3783-8952b8f2f624149239ee53cac5145b79bec5f862fde79ddb48c056480fb4a76e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjso.2930140413$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjso.2930140413$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7442263$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Goldman, Joel M.</creatorcontrib><creatorcontrib>Goren, Elihu N.</creatorcontrib><creatorcontrib>Cohen, Max H.</creatorcontrib><creatorcontrib>Webber, Bruce L.</creatorcontrib><creatorcontrib>Brennan, Murray F.</creatorcontrib><creatorcontrib>Robbins, Jacob</creatorcontrib><title>Anaplastic thyroid carcinoma: Long-term survival after radical surgery</title><title>Journal of surgical oncology</title><addtitle>J. Surg. Oncol</addtitle><description>Anaplastic carcinoma of the thyroid is a highly malignant disease with few survivors over one year. Radical surgery and laryngectomy are usually considered contraindicated. A 50‐year‐old woman with a history of papillary carcinoma treated with external radiation developed anaplastic giant‐cell carcinoma of the thyroid invading the soft tissues of the neck including the larynx. Since surgery was felt to represent her only chance for survival, she underwent laryngopharyngectomy, right radical‐neck dissection, and pharyngeal reconstruction. Three years after the surgery was performed, she is living an active life with only minor handicaps. Nevertheless, multiple nodules were noted in her lungs on recent tomographic examination. Our experience with this woman suggests that there is a role for radical surgery and laryngectomy in selected cases of anaplastic carcinoma.</description><subject>anaplastic carcinoma</subject><subject>Carcinoma - etiology</subject><subject>Carcinoma - surgery</subject><subject>Carcinoma, Papillary - complications</subject><subject>Female</subject><subject>Humans</subject><subject>Laryngectomy</subject><subject>laryngopharyngectomy</subject><subject>Middle Aged</subject><subject>Neck Dissection</subject><subject>Pharyngectomy</subject><subject>Prognosis</subject><subject>thyroid</subject><subject>Thyroid Neoplasms - etiology</subject><subject>Thyroid Neoplasms - surgery</subject><issn>0022-4790</issn><issn>1096-9098</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1980</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtPAjEUhRujQUS37kxm5W6wz-nUHUHBB8ICjcum0-lgcYbBdkD599ZAMK5c3dx7zvlucgA4R7CLIMRXc193sSAQUUgROQBtBEUSCyjSQ9AOBhxTLuAxOPF-DiEUIqEt0OKUYpyQNhj0FmpZKt9YHTVvG1fbPNLKabuoK3UdjerFLG6MqyK_cmu7VmWkirBHTuVWhy2cZ8ZtTsFRoUpvznazA14Gt8_9u3g0Gd73e6NYE56SOBUMZ2mBiwRTRAUmwhhGtNIMUZZxkRnNijTBRW64yPOMphqyhKawyKjiiSEdcLnlLl39sTK-kZX12pSlWph65SVn4Q-mOBi7W6N2tffOFHLpbKXcRiIof4qToTj5W1wIXOzIq6wy-d6-ayroYqt_2tJs_qHJh-nkDzveZq1vzNc-q9y7TDjhTL6Oh3I8HfIndoPkI_kGsp-JDg</recordid><startdate>19800101</startdate><enddate>19800101</enddate><creator>Goldman, Joel M.</creator><creator>Goren, Elihu N.</creator><creator>Cohen, Max H.</creator><creator>Webber, Bruce L.</creator><creator>Brennan, Murray F.</creator><creator>Robbins, Jacob</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19800101</creationdate><title>Anaplastic thyroid carcinoma: Long-term survival after radical surgery</title><author>Goldman, Joel M. ; Goren, Elihu N. ; Cohen, Max H. ; Webber, Bruce L. ; Brennan, Murray F. ; Robbins, Jacob</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3783-8952b8f2f624149239ee53cac5145b79bec5f862fde79ddb48c056480fb4a76e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1980</creationdate><topic>anaplastic carcinoma</topic><topic>Carcinoma - etiology</topic><topic>Carcinoma - surgery</topic><topic>Carcinoma, Papillary - complications</topic><topic>Female</topic><topic>Humans</topic><topic>Laryngectomy</topic><topic>laryngopharyngectomy</topic><topic>Middle Aged</topic><topic>Neck Dissection</topic><topic>Pharyngectomy</topic><topic>Prognosis</topic><topic>thyroid</topic><topic>Thyroid Neoplasms - etiology</topic><topic>Thyroid Neoplasms - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Goldman, Joel M.</creatorcontrib><creatorcontrib>Goren, Elihu N.</creatorcontrib><creatorcontrib>Cohen, Max H.</creatorcontrib><creatorcontrib>Webber, Bruce L.</creatorcontrib><creatorcontrib>Brennan, Murray F.</creatorcontrib><creatorcontrib>Robbins, Jacob</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of surgical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Goldman, Joel M.</au><au>Goren, Elihu N.</au><au>Cohen, Max H.</au><au>Webber, Bruce L.</au><au>Brennan, Murray F.</au><au>Robbins, Jacob</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Anaplastic thyroid carcinoma: Long-term survival after radical surgery</atitle><jtitle>Journal of surgical oncology</jtitle><addtitle>J. Surg. Oncol</addtitle><date>1980-01-01</date><risdate>1980</risdate><volume>14</volume><issue>4</issue><spage>389</spage><epage>394</epage><pages>389-394</pages><issn>0022-4790</issn><eissn>1096-9098</eissn><abstract>Anaplastic carcinoma of the thyroid is a highly malignant disease with few survivors over one year. Radical surgery and laryngectomy are usually considered contraindicated. A 50‐year‐old woman with a history of papillary carcinoma treated with external radiation developed anaplastic giant‐cell carcinoma of the thyroid invading the soft tissues of the neck including the larynx. Since surgery was felt to represent her only chance for survival, she underwent laryngopharyngectomy, right radical‐neck dissection, and pharyngeal reconstruction. Three years after the surgery was performed, she is living an active life with only minor handicaps. Nevertheless, multiple nodules were noted in her lungs on recent tomographic examination. Our experience with this woman suggests that there is a role for radical surgery and laryngectomy in selected cases of anaplastic carcinoma.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>7442263</pmid><doi>10.1002/jso.2930140413</doi><tpages>6</tpages></addata></record> |
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subjects | anaplastic carcinoma Carcinoma - etiology Carcinoma - surgery Carcinoma, Papillary - complications Female Humans Laryngectomy laryngopharyngectomy Middle Aged Neck Dissection Pharyngectomy Prognosis thyroid Thyroid Neoplasms - etiology Thyroid Neoplasms - surgery |
title | Anaplastic thyroid carcinoma: Long-term survival after radical surgery |
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