Utilization of Acetate in Experimental Diabetes
IT is well known that acetic acid occupies an important place in the intermediary metabolism, and that the participation of this substance in many reactions requires the activation of the acetate molecule. It is now generally considered that ‘active acetate’ corresponds to acetyl coenzyme A . Theref...
Gespeichert in:
| Veröffentlicht in: | Nature (London) 1953-11, Vol.172 (4386), p.961-961 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 961 |
|---|---|
| container_issue | 4386 |
| container_start_page | 961 |
| container_title | Nature (London) |
| container_volume | 172 |
| creator | CIARANFI, E. FONNESU, A. |
| description | IT is well known that acetic acid occupies an important place in the intermediary metabolism, and that the participation of this substance in many reactions requires the activation of the acetate molecule. It is now generally considered that ‘active acetate’ corresponds to acetyl coenzyme
A
. Therefore, it appears reasonable to assume that a reduction of the acetylation of coenzyme
A
, that is, of the formation of ‘active acetate’, would lead to the accumulation of acetic acid. |
| doi_str_mv | 10.1038/172961a0 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_75375616</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>75375616</sourcerecordid><originalsourceid>FETCH-LOGICAL-c349t-6a1df9d3ef3cd2351bf344690b890adb91ca3a7fcf8ca1aaa7a4339df5170b1d3</originalsourceid><addsrcrecordid>eNplkEtLw0AUhQdRbK2Cv0CyEl3Ezs1MZpJlqfUBBTd2PdzMQ1LSpGYmoP56Rxpx4eouzsfHuYeQS6B3QFkxB5mVApAekSlwKVIuCnlMppRmRUoLJibkzPstpTQHyU_JBBgAZIxPyXwT6qb-wlB3bdK5ZKFtwGCTuk1WH3vb1zvbBmyS-xorG6w_JycOG28vxjsjm4fV6_IpXb88Pi8X61QzXoZUIBhXGmYd0yZjOVSOcS5KWhUlRVOVoJGhdNoVGgERJXLGSuNiQVqBYTNyffDu--59sD6oXe21bRpsbTd4JXMmcwEigjcHUPed9711ah9LY_-pgKqfcdTvOBG9Gp1DtbPmDxzXiMDtAfAxat9sr7bd0Lfxz_-yb4cza2Q</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>75375616</pqid></control><display><type>article</type><title>Utilization of Acetate in Experimental Diabetes</title><source>MEDLINE</source><source>SpringerLink Journals</source><source>Nature Journals Online</source><creator>CIARANFI, E. ; FONNESU, A.</creator><creatorcontrib>CIARANFI, E. ; FONNESU, A.</creatorcontrib><description>IT is well known that acetic acid occupies an important place in the intermediary metabolism, and that the participation of this substance in many reactions requires the activation of the acetate molecule. It is now generally considered that ‘active acetate’ corresponds to acetyl coenzyme
A
. Therefore, it appears reasonable to assume that a reduction of the acetylation of coenzyme
A
, that is, of the formation of ‘active acetate’, would lead to the accumulation of acetic acid.</description><identifier>ISSN: 0028-0836</identifier><identifier>EISSN: 1476-4687</identifier><identifier>DOI: 10.1038/172961a0</identifier><identifier>PMID: 13111234</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Acetates - metabolism ; Animals ; Diabetes Mellitus, Experimental ; Humanities and Social Sciences ; letter ; multidisciplinary ; Old Medline ; Science ; Science (multidisciplinary)</subject><ispartof>Nature (London), 1953-11, Vol.172 (4386), p.961-961</ispartof><rights>Springer Nature Limited 1953</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c349t-6a1df9d3ef3cd2351bf344690b890adb91ca3a7fcf8ca1aaa7a4339df5170b1d3</citedby><cites>FETCH-LOGICAL-c349t-6a1df9d3ef3cd2351bf344690b890adb91ca3a7fcf8ca1aaa7a4339df5170b1d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/172961a0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/172961a0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/13111234$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>CIARANFI, E.</creatorcontrib><creatorcontrib>FONNESU, A.</creatorcontrib><title>Utilization of Acetate in Experimental Diabetes</title><title>Nature (London)</title><addtitle>Nature</addtitle><addtitle>Nature</addtitle><description>IT is well known that acetic acid occupies an important place in the intermediary metabolism, and that the participation of this substance in many reactions requires the activation of the acetate molecule. It is now generally considered that ‘active acetate’ corresponds to acetyl coenzyme
A
. Therefore, it appears reasonable to assume that a reduction of the acetylation of coenzyme
A
, that is, of the formation of ‘active acetate’, would lead to the accumulation of acetic acid.</description><subject>Acetates - metabolism</subject><subject>Animals</subject><subject>Diabetes Mellitus, Experimental</subject><subject>Humanities and Social Sciences</subject><subject>letter</subject><subject>multidisciplinary</subject><subject>Old Medline</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><issn>0028-0836</issn><issn>1476-4687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1953</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkEtLw0AUhQdRbK2Cv0CyEl3Ezs1MZpJlqfUBBTd2PdzMQ1LSpGYmoP56Rxpx4eouzsfHuYeQS6B3QFkxB5mVApAekSlwKVIuCnlMppRmRUoLJibkzPstpTQHyU_JBBgAZIxPyXwT6qb-wlB3bdK5ZKFtwGCTuk1WH3vb1zvbBmyS-xorG6w_JycOG28vxjsjm4fV6_IpXb88Pi8X61QzXoZUIBhXGmYd0yZjOVSOcS5KWhUlRVOVoJGhdNoVGgERJXLGSuNiQVqBYTNyffDu--59sD6oXe21bRpsbTd4JXMmcwEigjcHUPed9711ah9LY_-pgKqfcdTvOBG9Gp1DtbPmDxzXiMDtAfAxat9sr7bd0Lfxz_-yb4cza2Q</recordid><startdate>19531121</startdate><enddate>19531121</enddate><creator>CIARANFI, E.</creator><creator>FONNESU, A.</creator><general>Nature Publishing Group UK</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19531121</creationdate><title>Utilization of Acetate in Experimental Diabetes</title><author>CIARANFI, E. ; FONNESU, A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c349t-6a1df9d3ef3cd2351bf344690b890adb91ca3a7fcf8ca1aaa7a4339df5170b1d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1953</creationdate><topic>Acetates - metabolism</topic><topic>Animals</topic><topic>Diabetes Mellitus, Experimental</topic><topic>Humanities and Social Sciences</topic><topic>letter</topic><topic>multidisciplinary</topic><topic>Old Medline</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>CIARANFI, E.</creatorcontrib><creatorcontrib>FONNESU, A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Nature (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>CIARANFI, E.</au><au>FONNESU, A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Utilization of Acetate in Experimental Diabetes</atitle><jtitle>Nature (London)</jtitle><stitle>Nature</stitle><addtitle>Nature</addtitle><date>1953-11-21</date><risdate>1953</risdate><volume>172</volume><issue>4386</issue><spage>961</spage><epage>961</epage><pages>961-961</pages><issn>0028-0836</issn><eissn>1476-4687</eissn><abstract>IT is well known that acetic acid occupies an important place in the intermediary metabolism, and that the participation of this substance in many reactions requires the activation of the acetate molecule. It is now generally considered that ‘active acetate’ corresponds to acetyl coenzyme
A
. Therefore, it appears reasonable to assume that a reduction of the acetylation of coenzyme
A
, that is, of the formation of ‘active acetate’, would lead to the accumulation of acetic acid.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>13111234</pmid><doi>10.1038/172961a0</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0028-0836 |
| ispartof | Nature (London), 1953-11, Vol.172 (4386), p.961-961 |
| issn | 0028-0836 1476-4687 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_75375616 |
| source | MEDLINE; SpringerLink Journals; Nature Journals Online |
| subjects | Acetates - metabolism Animals Diabetes Mellitus, Experimental Humanities and Social Sciences letter multidisciplinary Old Medline Science Science (multidisciplinary) |
| title | Utilization of Acetate in Experimental Diabetes |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-14T09%3A32%3A23IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Utilization%20of%20Acetate%20in%20Experimental%20Diabetes&rft.jtitle=Nature%20(London)&rft.au=CIARANFI,%20E.&rft.date=1953-11-21&rft.volume=172&rft.issue=4386&rft.spage=961&rft.epage=961&rft.pages=961-961&rft.issn=0028-0836&rft.eissn=1476-4687&rft_id=info:doi/10.1038/172961a0&rft_dat=%3Cproquest_cross%3E75375616%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=75375616&rft_id=info:pmid/13111234&rfr_iscdi=true |