A prediction of cell differentiation and proliferation within a collagen–glycosaminoglycan scaffold subjected to mechanical strain and perfusive fluid flow

Abstract Mesenchymal stem cell (MSC) differentiation can be influenced by biophysical stimuli imparted by the host scaffold. Yet, causal relationships linking scaffold strain magnitudes and inlet fluid velocities to specific cell responses are thus far underdeveloped. This investigation attempted to...

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Veröffentlicht in:Journal of biomechanics 2010-03, Vol.43 (4), p.618-626
Hauptverfasser: Stops, A.J.F, Heraty, K.B, Browne, M, O'Brien, F.J, McHugh, P.E
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Sprache:eng
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