Ultrasonic effects on alveolar macrophages in suspension
Rabbit alveolar macrophages in suspension were exposed to 5 or 10 min of continuous 2‐MHz ultrasound with 5, 10, and 15 W/cm2 spatial average intensities. Viability as determined by dye exclusion decreased with increasing intensity. Pressure experiments indicated that this was a result of acoustic c...
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| Veröffentlicht in: | Journal of clinical ultrasound 1980-12, Vol.8 (6), p.465-472 |
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| container_title | Journal of clinical ultrasound |
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| creator | Leake, Eva S. Wright, Mary Jo Kremkau, Frederick W. |
| description | Rabbit alveolar macrophages in suspension were exposed to 5 or 10 min of continuous 2‐MHz ultrasound with 5, 10, and 15 W/cm2 spatial average intensities. Viability as determined by dye exclusion decreased with increasing intensity. Pressure experiments indicated that this was a result of acoustic cavitation. Ultrasound induced clumping of cells and often reduced membrane ruffling. Some cells were disintegrated. Cells that appeared to be otherwise intact had swollen mitochondria with ruptured cristae. |
| doi_str_mv | 10.1002/jcu.1870080604 |
| format | Article |
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Viability as determined by dye exclusion decreased with increasing intensity. Pressure experiments indicated that this was a result of acoustic cavitation. Ultrasound induced clumping of cells and often reduced membrane ruffling. Some cells were disintegrated. Cells that appeared to be otherwise intact had swollen mitochondria with ruptured cristae.</description><identifier>ISSN: 0091-2751</identifier><identifier>EISSN: 1097-0096</identifier><identifier>DOI: 10.1002/jcu.1870080604</identifier><identifier>PMID: 6777403</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Animals ; Cavitation ; Cell Membrane - ultrastructure ; Cell Survival ; Macrophages ; Macrophages - ultrastructure ; Microscopy, Electron ; Microscopy, Electron, Scanning ; Mitochondria - ultrastructure ; Pulmonary Alveoli - cytology ; Rabbits ; Ultrasonics ; Ultrastructure ; Viability</subject><ispartof>Journal of clinical ultrasound, 1980-12, Vol.8 (6), p.465-472</ispartof><rights>Copyright © 1980 Wiley Periodicals, Inc., A Wiley Company</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3784-50099cb6a2d05add9b124c1c12ed628515c03ec9be8c118b8e3cebe39ce0406a3</citedby><cites>FETCH-LOGICAL-c3784-50099cb6a2d05add9b124c1c12ed628515c03ec9be8c118b8e3cebe39ce0406a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjcu.1870080604$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjcu.1870080604$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6777403$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Leake, Eva S.</creatorcontrib><creatorcontrib>Wright, Mary Jo</creatorcontrib><creatorcontrib>Kremkau, Frederick W.</creatorcontrib><title>Ultrasonic effects on alveolar macrophages in suspension</title><title>Journal of clinical ultrasound</title><addtitle>J. Clin. Ultrasound</addtitle><description>Rabbit alveolar macrophages in suspension were exposed to 5 or 10 min of continuous 2‐MHz ultrasound with 5, 10, and 15 W/cm2 spatial average intensities. Viability as determined by dye exclusion decreased with increasing intensity. Pressure experiments indicated that this was a result of acoustic cavitation. Ultrasound induced clumping of cells and often reduced membrane ruffling. Some cells were disintegrated. Cells that appeared to be otherwise intact had swollen mitochondria with ruptured cristae.</description><subject>Animals</subject><subject>Cavitation</subject><subject>Cell Membrane - ultrastructure</subject><subject>Cell Survival</subject><subject>Macrophages</subject><subject>Macrophages - ultrastructure</subject><subject>Microscopy, Electron</subject><subject>Microscopy, Electron, Scanning</subject><subject>Mitochondria - ultrastructure</subject><subject>Pulmonary Alveoli - cytology</subject><subject>Rabbits</subject><subject>Ultrasonics</subject><subject>Ultrastructure</subject><subject>Viability</subject><issn>0091-2751</issn><issn>1097-0096</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1980</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkD1PwzAYhC0EKqWwsiFlYkt5HccfGVGBAqqAgaqIxXKcN5CSjxInQP89QamKmJhuuLtHpyPkmMKYAgRnS9uOqZIACgSEO2RIIZI-QCR2ybAT6geS031y4NwSAATnfEAGQkoZAhsSNc-b2riqzKyHaYq2cV5Veib_wCo3tVcYW1erV_OCzstKz7VuhaXLqvKQ7KUmd3i00RGZX10-Tq792f30ZnI-8y2TKvR5NyGysTBBAtwkSRTTILTU0gATEShOuQWGNopRWUpVrJBZjJFFFiEEYdiInPbcVV29t-gaXWTOYp6bEqvWacmZiAIBXXDcB7vBztWY6lWdFaZeawr65yrdXaV_r-oKJxtyGxeYbOObbzo_6v3PLMf1PzR9O5n_Yft9N3MNfm27pn7r8Exyvbib6umFunhaPCj9zL4BWWqEfg</recordid><startdate>198012</startdate><enddate>198012</enddate><creator>Leake, Eva S.</creator><creator>Wright, Mary Jo</creator><creator>Kremkau, Frederick W.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198012</creationdate><title>Ultrasonic effects on alveolar macrophages in suspension</title><author>Leake, Eva S. ; Wright, Mary Jo ; Kremkau, Frederick W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3784-50099cb6a2d05add9b124c1c12ed628515c03ec9be8c118b8e3cebe39ce0406a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1980</creationdate><topic>Animals</topic><topic>Cavitation</topic><topic>Cell Membrane - ultrastructure</topic><topic>Cell Survival</topic><topic>Macrophages</topic><topic>Macrophages - ultrastructure</topic><topic>Microscopy, Electron</topic><topic>Microscopy, Electron, Scanning</topic><topic>Mitochondria - ultrastructure</topic><topic>Pulmonary Alveoli - cytology</topic><topic>Rabbits</topic><topic>Ultrasonics</topic><topic>Ultrastructure</topic><topic>Viability</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Leake, Eva S.</creatorcontrib><creatorcontrib>Wright, Mary Jo</creatorcontrib><creatorcontrib>Kremkau, Frederick W.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical ultrasound</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Leake, Eva S.</au><au>Wright, Mary Jo</au><au>Kremkau, Frederick W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ultrasonic effects on alveolar macrophages in suspension</atitle><jtitle>Journal of clinical ultrasound</jtitle><addtitle>J. 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| ispartof | Journal of clinical ultrasound, 1980-12, Vol.8 (6), p.465-472 |
| issn | 0091-2751 1097-0096 |
| language | eng |
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| source | MEDLINE; Wiley Online Library |
| subjects | Animals Cavitation Cell Membrane - ultrastructure Cell Survival Macrophages Macrophages - ultrastructure Microscopy, Electron Microscopy, Electron, Scanning Mitochondria - ultrastructure Pulmonary Alveoli - cytology Rabbits Ultrasonics Ultrastructure Viability |
| title | Ultrasonic effects on alveolar macrophages in suspension |
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