Microstructures and properties of cancellous bone of avascular necrosis of femoral heads

The aim of this study is to investigate microscopic structure and characterize cancellous bone of avascular necrosis of the femoral head (ANFH). The rabbit model of the ANFH is established. The histopathologic features are studied successfully. The differences between the steroidinjection group (S.G...

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Veröffentlicht in:Acta mechanica Sinica 2010, Vol.26 (1), p.13-19
Hauptverfasser: Yao, Xuefeng, Wang, Peng, Dai, Ruchun, Yeh, Hsien Yang
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creator Yao, Xuefeng
Wang, Peng
Dai, Ruchun
Yeh, Hsien Yang
description The aim of this study is to investigate microscopic structure and characterize cancellous bone of avascular necrosis of the femoral head (ANFH). The rabbit model of the ANFH is established. The histopathologic features are studied successfully. The differences between the steroidinjection group (S.G.) and the controlled group (C.G.) are examined, including the weight of rabbits, the hematological examination and the three-dimensional stnactures. It is found that the plasma levels of cholesterol (CHO), high-density lipoprotein (HDL) and low-density lipoprotein (LDL) in S.G. are lower than those in C.G. when the triglyceride (TG) increased in the S.G.; but the bone mineral content (BMC) and the structural model index (SMI) of the organ and tissue decreased significantly in S.G. Three-dimensional structures of the femoral head are obtained using micro-computed tomography (CT) scanning and the mechanical model is established to analyze the influences of these structural changes on the mechanical properties of the cancellous bone.
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subjects Bone mineral content
Bones
Bulk molding compounds
Cholesterol
Classical and Continuum Physics
Computational Intelligence
Computed tomography
Density
Engineering
Engineering Fluid Dynamics
Lipoproteins
Mechanical properties
Necrosis
Organs
Rabbits
Research Paper
Scanning
Steroids
Structural models
Theoretical and Applied Mechanics
Triglycerides
低密度脂蛋白
力学性能
微结构
松质骨
组织学特征
股骨头坏死
高密度脂蛋白
title Microstructures and properties of cancellous bone of avascular necrosis of femoral heads
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