Plantaricin A, a peptide pheromone produced by Lactobacillus plantarum, permeabilizes the cell membrane of both normal and cancerous lymphocytes and neuronal cells

Antimicrobial peptides produced by multicellular organisms protect against pathogenic microorganisms, whereas such peptides produced by bacteria provide an ecological advantage over competitors. Certain antimicrobial peptides of metazoan origin are also toxic to eukaryotic cells, with preference for...

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Veröffentlicht in:	Peptides (New York, N.Y. : 1980) N.Y. : 1980), 2010-07, Vol.31 (7), p.1237-1244
Hauptverfasser:	Sand, Sverre L., Oppegård, Camilla, Ohara, Shinya, Iijima, Toshio, Naderi, Soheil, Blomhoff, Heidi K., Nissen-Meyer, Jon, Sand, Olav
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - metabolism Antineoplastic Agents - pharmacology Bacteria Bacteriocins - biosynthesis Bacteriocins - pharmacology Biological and medical sciences Cell lysis Cell Membrane - drug effects Cell Membrane - metabolism Cell Membrane Permeability - drug effects Flow Cytometry Fundamental and applied biological sciences. Psychology Human Humans Jurkat Cells Lactobacillus plantarum Lactobacillus plantarum - metabolism Leukemia - metabolism Leukemia - pathology Leukemias Lymphocytes Lymphocytes - cytology Lymphocytes - drug effects Lymphocytes - metabolism Membrane permeabilization Membranes Metazoa Mice Monitors Neuronal cells Neurons - drug effects Neurons - metabolism Peptides Pheromones - biosynthesis Plantaricin A (PlnA) Rats Vertebrates: endocrinology
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