Priming and Inhibitory Activities of RNAs for the Influenza Viral Transcriptase Do not Require Base Pairing with the Virion Template RNA

Capped ribopolymers lacking a sequence complementary to the common 3′ end of the influenza virion RNA segments effectively stimulated transcription of these RNAs by the virion-associated transcriptase. Thus, stimulation of transcription results not from hydrogen bonding between the capped RNA and th...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 1980-10, Vol.77 (10), p.5874-5878
Hauptverfasser: Krug, Robert M., Broni, Barbara A., LaFiandra, Alba J., Morgan, Maureen A., Shatkin, Aaron J.
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Sprache:eng
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