A Longitudinal Study of Urinary Excretion of N,N,-Dimethyltryptamine in Psychotic Patients
The excretion of N,N,-dimethlytryptamine (DMT) has been measured in longitudinal studies of five patients with schizophrenic illnesses and in four patients with rapidly or slowly cycling manic-depressive illness. The excretion of DMT was frequently raised in patients when they were psychotic but was...
Gespeichert in:
| Veröffentlicht in: | British journal of psychiatry 1980-09, Vol.137 (3), p.236-239 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 239 |
|---|---|
| container_issue | 3 |
| container_start_page | 236 |
| container_title | British journal of psychiatry |
| container_volume | 137 |
| creator | Checkley, S. A. Murray, R. M. Oon, M. C. H. Rodnight, R. Birley, J. L. T. |
| description | The excretion of N,N,-dimethlytryptamine (DMT) has been measured in longitudinal studies of five patients with schizophrenic illnesses and in four patients with rapidly or slowly cycling manic-depressive illness. The excretion of DMT was frequently raised in patients when they were psychotic but was usually normal when they had recovered. However, rapid changes in the severity of illness or sudden switches from one mood state to another were not accompanied by changes in the excretion of DMT. These findings contrast with the immediate hallucinogenic effects of an injection of DMT, and suggest that the extracerebral production of DMT (as measured by its urinary excretion) does not provoke the experience of hallucinations in psychotic patients. |
| doi_str_mv | 10.1192/bjp.137.3.236 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_75344872</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cupid>10_1192_bjp_137_3_236</cupid><sourcerecordid>75344872</sourcerecordid><originalsourceid>FETCH-LOGICAL-c286t-8dd0f3bd00a5fbb926d20e1a3fe6f81dc5ec3075eba315497f8d7f1120e7d6453</originalsourceid><addsrcrecordid>eNp1kMtLAzEQh4MotVaPHoX14qnb5rG72R6l1geUKqgXLyGbR5uyL5Msuv-9KS2CB08zk_n4DfkAuERwgtAMT4ttO0GETsgEk-wIDFFCcYySLD0GQwghjRFO4Sk4c24bRpJgOgCDjFIK4WwIPm6jZVOvje-kqXkZvYamjxodvdsw2z5afAurvGnq3eNqvBrHd6ZSftOX3vat55WpVWTq6MX1YtN4I6IX7o2qvTsHJ5qXTl0c6gi83y_e5o_x8vnhaX67jAXOMx_nUkJNCgkhT3VRzHAmMVSIE60ynSMpUiUIpKkqOEFpMqM6l1QjFCAqsyQlI3Czz21t89kp51llnFBlyWvVdI7RlCRJTnEA4z0obOOcVZq11lThkwxBtnPJgksWXDLCgsvAXx2Cu6JS8pc-yAv76_1-Y9abL2MVs6LdafiTMT3c5FVhjVwrtm06G1S7f67-AK2Qixs</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>75344872</pqid></control><display><type>article</type><title>A Longitudinal Study of Urinary Excretion of N,N,-Dimethyltryptamine in Psychotic Patients</title><source>MEDLINE</source><source>Cambridge Journals</source><creator>Checkley, S. A. ; Murray, R. M. ; Oon, M. C. H. ; Rodnight, R. ; Birley, J. L. T.</creator><creatorcontrib>Checkley, S. A. ; Murray, R. M. ; Oon, M. C. H. ; Rodnight, R. ; Birley, J. L. T.</creatorcontrib><description>The excretion of N,N,-dimethlytryptamine (DMT) has been measured in longitudinal studies of five patients with schizophrenic illnesses and in four patients with rapidly or slowly cycling manic-depressive illness. The excretion of DMT was frequently raised in patients when they were psychotic but was usually normal when they had recovered. However, rapid changes in the severity of illness or sudden switches from one mood state to another were not accompanied by changes in the excretion of DMT. These findings contrast with the immediate hallucinogenic effects of an injection of DMT, and suggest that the extracerebral production of DMT (as measured by its urinary excretion) does not provoke the experience of hallucinations in psychotic patients.</description><identifier>ISSN: 0007-1250</identifier><identifier>EISSN: 1472-1465</identifier><identifier>DOI: 10.1192/bjp.137.3.236</identifier><identifier>PMID: 6777009</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Bipolar Disorder - psychology ; Bipolar Disorder - urine ; Female ; Humans ; Male ; N,N-Dimethyltryptamine - urine ; Schizophrenia - urine ; Schizophrenic Psychology ; Tryptamines - urine</subject><ispartof>British journal of psychiatry, 1980-09, Vol.137 (3), p.236-239</ispartof><rights>Copyright © Royal College of Psychiatrists, 1980</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c286t-8dd0f3bd00a5fbb926d20e1a3fe6f81dc5ec3075eba315497f8d7f1120e7d6453</citedby><cites>FETCH-LOGICAL-c286t-8dd0f3bd00a5fbb926d20e1a3fe6f81dc5ec3075eba315497f8d7f1120e7d6453</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.cambridge.org/core/product/identifier/S0007125000105409/type/journal_article$$EHTML$$P50$$Gcambridge$$H</linktohtml><link.rule.ids>164,314,776,780,27901,27902,55603</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6777009$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Checkley, S. A.</creatorcontrib><creatorcontrib>Murray, R. M.</creatorcontrib><creatorcontrib>Oon, M. C. H.</creatorcontrib><creatorcontrib>Rodnight, R.</creatorcontrib><creatorcontrib>Birley, J. L. T.</creatorcontrib><title>A Longitudinal Study of Urinary Excretion of N,N,-Dimethyltryptamine in Psychotic Patients</title><title>British journal of psychiatry</title><addtitle>Br J Psychiatry</addtitle><description>The excretion of N,N,-dimethlytryptamine (DMT) has been measured in longitudinal studies of five patients with schizophrenic illnesses and in four patients with rapidly or slowly cycling manic-depressive illness. The excretion of DMT was frequently raised in patients when they were psychotic but was usually normal when they had recovered. However, rapid changes in the severity of illness or sudden switches from one mood state to another were not accompanied by changes in the excretion of DMT. These findings contrast with the immediate hallucinogenic effects of an injection of DMT, and suggest that the extracerebral production of DMT (as measured by its urinary excretion) does not provoke the experience of hallucinations in psychotic patients.</description><subject>Bipolar Disorder - psychology</subject><subject>Bipolar Disorder - urine</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>N,N-Dimethyltryptamine - urine</subject><subject>Schizophrenia - urine</subject><subject>Schizophrenic Psychology</subject><subject>Tryptamines - urine</subject><issn>0007-1250</issn><issn>1472-1465</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1980</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kMtLAzEQh4MotVaPHoX14qnb5rG72R6l1geUKqgXLyGbR5uyL5Msuv-9KS2CB08zk_n4DfkAuERwgtAMT4ttO0GETsgEk-wIDFFCcYySLD0GQwghjRFO4Sk4c24bRpJgOgCDjFIK4WwIPm6jZVOvje-kqXkZvYamjxodvdsw2z5afAurvGnq3eNqvBrHd6ZSftOX3vat55WpVWTq6MX1YtN4I6IX7o2qvTsHJ5qXTl0c6gi83y_e5o_x8vnhaX67jAXOMx_nUkJNCgkhT3VRzHAmMVSIE60ynSMpUiUIpKkqOEFpMqM6l1QjFCAqsyQlI3Czz21t89kp51llnFBlyWvVdI7RlCRJTnEA4z0obOOcVZq11lThkwxBtnPJgksWXDLCgsvAXx2Cu6JS8pc-yAv76_1-Y9abL2MVs6LdafiTMT3c5FVhjVwrtm06G1S7f67-AK2Qixs</recordid><startdate>198009</startdate><enddate>198009</enddate><creator>Checkley, S. A.</creator><creator>Murray, R. M.</creator><creator>Oon, M. C. H.</creator><creator>Rodnight, R.</creator><creator>Birley, J. L. T.</creator><general>Cambridge University Press</general><general>RCP</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198009</creationdate><title>A Longitudinal Study of Urinary Excretion of N,N,-Dimethyltryptamine in Psychotic Patients</title><author>Checkley, S. A. ; Murray, R. M. ; Oon, M. C. H. ; Rodnight, R. ; Birley, J. L. T.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c286t-8dd0f3bd00a5fbb926d20e1a3fe6f81dc5ec3075eba315497f8d7f1120e7d6453</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1980</creationdate><topic>Bipolar Disorder - psychology</topic><topic>Bipolar Disorder - urine</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>N,N-Dimethyltryptamine - urine</topic><topic>Schizophrenia - urine</topic><topic>Schizophrenic Psychology</topic><topic>Tryptamines - urine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Checkley, S. A.</creatorcontrib><creatorcontrib>Murray, R. M.</creatorcontrib><creatorcontrib>Oon, M. C. H.</creatorcontrib><creatorcontrib>Rodnight, R.</creatorcontrib><creatorcontrib>Birley, J. L. T.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Checkley, S. A.</au><au>Murray, R. M.</au><au>Oon, M. C. H.</au><au>Rodnight, R.</au><au>Birley, J. L. T.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Longitudinal Study of Urinary Excretion of N,N,-Dimethyltryptamine in Psychotic Patients</atitle><jtitle>British journal of psychiatry</jtitle><addtitle>Br J Psychiatry</addtitle><date>1980-09</date><risdate>1980</risdate><volume>137</volume><issue>3</issue><spage>236</spage><epage>239</epage><pages>236-239</pages><issn>0007-1250</issn><eissn>1472-1465</eissn><abstract>The excretion of N,N,-dimethlytryptamine (DMT) has been measured in longitudinal studies of five patients with schizophrenic illnesses and in four patients with rapidly or slowly cycling manic-depressive illness. The excretion of DMT was frequently raised in patients when they were psychotic but was usually normal when they had recovered. However, rapid changes in the severity of illness or sudden switches from one mood state to another were not accompanied by changes in the excretion of DMT. These findings contrast with the immediate hallucinogenic effects of an injection of DMT, and suggest that the extracerebral production of DMT (as measured by its urinary excretion) does not provoke the experience of hallucinations in psychotic patients.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>6777009</pmid><doi>10.1192/bjp.137.3.236</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0007-1250 |
| ispartof | British journal of psychiatry, 1980-09, Vol.137 (3), p.236-239 |
| issn | 0007-1250 1472-1465 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_75344872 |
| source | MEDLINE; Cambridge Journals |
| subjects | Bipolar Disorder - psychology Bipolar Disorder - urine Female Humans Male N,N-Dimethyltryptamine - urine Schizophrenia - urine Schizophrenic Psychology Tryptamines - urine |
| title | A Longitudinal Study of Urinary Excretion of N,N,-Dimethyltryptamine in Psychotic Patients |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T20%3A42%3A52IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20Longitudinal%20Study%20of%20Urinary%20Excretion%20of%20N,N,-Dimethyltryptamine%20in%20Psychotic%20Patients&rft.jtitle=British%20journal%20of%20psychiatry&rft.au=Checkley,%20S.%20A.&rft.date=1980-09&rft.volume=137&rft.issue=3&rft.spage=236&rft.epage=239&rft.pages=236-239&rft.issn=0007-1250&rft.eissn=1472-1465&rft_id=info:doi/10.1192/bjp.137.3.236&rft_dat=%3Cproquest_cross%3E75344872%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=75344872&rft_id=info:pmid/6777009&rft_cupid=10_1192_bjp_137_3_236&rfr_iscdi=true |