Site-specific X-chromosome rearrangements from hybrid dysgenesis in Drosophila melanogaster
When the germ line of Drosophila males is destabilized by a syndrome known as hybrid dysgenesis, X-chromosome rearrangements are found in up to 10 percent of the gametes produced. Some of these aberrations are simple inversions, but many are complex multibreak rearrangements. Furthermore, most of th...
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| Veröffentlicht in: | Science (American Association for the Advancement of Science) 1980-10, Vol.210 (4468), p.427-429 |
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| container_issue | 4468 |
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| creator | Berg, R Engels, W.R Kreber, R.A |
| description | When the germ line of Drosophila males is destabilized by a syndrome known as hybrid dysgenesis, X-chromosome rearrangements are found in up to 10 percent of the gametes produced. Some of these aberrations are simple inversions, but many are complex multibreak rearrangements. Furthermore, most of the breakpoints fall into a few highly localized positions on the chromosome. These positions are mostly at points of intercalary heterochromatin and may vary from one strain to the next. The results suggest that they may represent points of insertion of mobile DNA sequences. |
| doi_str_mv | 10.1126/science.6776625 |
| format | Article |
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Some of these aberrations are simple inversions, but many are complex multibreak rearrangements. Furthermore, most of the breakpoints fall into a few highly localized positions on the chromosome. These positions are mostly at points of intercalary heterochromatin and may vary from one strain to the next. The results suggest that they may represent points of insertion of mobile DNA sequences.</description><identifier>ISSN: 0036-8075</identifier><identifier>EISSN: 1095-9203</identifier><identifier>DOI: 10.1126/science.6776625</identifier><identifier>PMID: 6776625</identifier><language>eng</language><publisher>United States: The American Association for the Advancement of Science</publisher><subject>animal breeding ; animal genetics ; Animals ; arthropods ; Chromatin ; Chromosome Inversion ; Chromosome Mapping ; Chromosomes ; DNA - genetics ; Drosophila ; Drosophila melanogaster - genetics ; entomology ; Female ; Genetics ; Germ cells ; Heterochromatin ; Hybridity ; Male ; Meiosis ; Polytene chromosomes ; Repetitive Sequences, Nucleic Acid ; Sex Chromosomes ; Translocation, Genetic ; X Chromosome</subject><ispartof>Science (American Association for the Advancement of Science), 1980-10, Vol.210 (4468), p.427-429</ispartof><rights>Copyright 1980 The American Association for the Advancement of Science</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c367t-670087665d5887490a607d0cd82d945147cc124a1e65b6b099207dc63a0ba54b3</citedby><cites>FETCH-LOGICAL-c367t-670087665d5887490a607d0cd82d945147cc124a1e65b6b099207dc63a0ba54b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/1684728$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/1684728$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,776,780,799,2871,2872,27903,27904,57995,58228</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6776625$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Berg, R</creatorcontrib><creatorcontrib>Engels, W.R</creatorcontrib><creatorcontrib>Kreber, R.A</creatorcontrib><title>Site-specific X-chromosome rearrangements from hybrid dysgenesis in Drosophila melanogaster</title><title>Science (American Association for the Advancement of Science)</title><addtitle>Science</addtitle><description>When the germ line of Drosophila males is destabilized by a syndrome known as hybrid dysgenesis, X-chromosome rearrangements are found in up to 10 percent of the gametes produced. 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The results suggest that they may represent points of insertion of mobile DNA sequences.</description><subject>animal breeding</subject><subject>animal genetics</subject><subject>Animals</subject><subject>arthropods</subject><subject>Chromatin</subject><subject>Chromosome Inversion</subject><subject>Chromosome Mapping</subject><subject>Chromosomes</subject><subject>DNA - genetics</subject><subject>Drosophila</subject><subject>Drosophila melanogaster - genetics</subject><subject>entomology</subject><subject>Female</subject><subject>Genetics</subject><subject>Germ cells</subject><subject>Heterochromatin</subject><subject>Hybridity</subject><subject>Male</subject><subject>Meiosis</subject><subject>Polytene chromosomes</subject><subject>Repetitive Sequences, Nucleic Acid</subject><subject>Sex Chromosomes</subject><subject>Translocation, Genetic</subject><subject>X Chromosome</subject><issn>0036-8075</issn><issn>1095-9203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1980</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkM1L7DAUxYM80fFj7UZ5Xbmr3jRN0iwf4ycILlQQXIQ0vZ2JTNsxt7OY_97IlCdcuIvfuYdzD2NnHK44L9Q1-YC9xyultVKF3GMzDkbmpgDxh80AhMor0PKQHRF9AiRmxAE7mOQz9vESRsxpjT60wWfvuV_GoRto6DCL6GJ0_QI77EfK2gSy5baOocmaLS2wRwqUhT67ielgvQwrl3W4cv2wcDRiPGH7rVsRnk77mL3d3b7OH_Kn5_vH-b-n3Aulx1xpgCrFkY2sKl0acAp0A76pisaUkpfae16UjqOStarBpOd045VwUDtZ1uKYXe5813H42iCNtgvkcZWS4LAhq6UotDE8Ca93Qp8CU8TWrmPoXNxaDvanTjvVaad-0sXFZL2pO2z-63_5-Y5_0jjEXztVlbqoEv67w60brFvEQPbtpQAu0mghtBHf2r2FSQ</recordid><startdate>19801024</startdate><enddate>19801024</enddate><creator>Berg, R</creator><creator>Engels, W.R</creator><creator>Kreber, R.A</creator><general>The American Association for the Advancement of Science</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19801024</creationdate><title>Site-specific X-chromosome rearrangements from hybrid dysgenesis in Drosophila melanogaster</title><author>Berg, R ; Engels, W.R ; Kreber, R.A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c367t-670087665d5887490a607d0cd82d945147cc124a1e65b6b099207dc63a0ba54b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1980</creationdate><topic>animal breeding</topic><topic>animal genetics</topic><topic>Animals</topic><topic>arthropods</topic><topic>Chromatin</topic><topic>Chromosome Inversion</topic><topic>Chromosome Mapping</topic><topic>Chromosomes</topic><topic>DNA - genetics</topic><topic>Drosophila</topic><topic>Drosophila melanogaster - genetics</topic><topic>entomology</topic><topic>Female</topic><topic>Genetics</topic><topic>Germ cells</topic><topic>Heterochromatin</topic><topic>Hybridity</topic><topic>Male</topic><topic>Meiosis</topic><topic>Polytene chromosomes</topic><topic>Repetitive Sequences, Nucleic Acid</topic><topic>Sex Chromosomes</topic><topic>Translocation, Genetic</topic><topic>X Chromosome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Berg, R</creatorcontrib><creatorcontrib>Engels, W.R</creatorcontrib><creatorcontrib>Kreber, R.A</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Science (American Association for the Advancement of Science)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Berg, R</au><au>Engels, W.R</au><au>Kreber, R.A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Site-specific X-chromosome rearrangements from hybrid dysgenesis in Drosophila melanogaster</atitle><jtitle>Science (American Association for the Advancement of Science)</jtitle><addtitle>Science</addtitle><date>1980-10-24</date><risdate>1980</risdate><volume>210</volume><issue>4468</issue><spage>427</spage><epage>429</epage><pages>427-429</pages><issn>0036-8075</issn><eissn>1095-9203</eissn><abstract>When the germ line of Drosophila males is destabilized by a syndrome known as hybrid dysgenesis, X-chromosome rearrangements are found in up to 10 percent of the gametes produced. Some of these aberrations are simple inversions, but many are complex multibreak rearrangements. Furthermore, most of the breakpoints fall into a few highly localized positions on the chromosome. These positions are mostly at points of intercalary heterochromatin and may vary from one strain to the next. The results suggest that they may represent points of insertion of mobile DNA sequences.</abstract><cop>United States</cop><pub>The American Association for the Advancement of Science</pub><pmid>6776625</pmid><doi>10.1126/science.6776625</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0036-8075 |
| ispartof | Science (American Association for the Advancement of Science), 1980-10, Vol.210 (4468), p.427-429 |
| issn | 0036-8075 1095-9203 |
| language | eng |
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| source | American Association for the Advancement of Science; Jstor Complete Legacy; MEDLINE |
| subjects | animal breeding animal genetics Animals arthropods Chromatin Chromosome Inversion Chromosome Mapping Chromosomes DNA - genetics Drosophila Drosophila melanogaster - genetics entomology Female Genetics Germ cells Heterochromatin Hybridity Male Meiosis Polytene chromosomes Repetitive Sequences, Nucleic Acid Sex Chromosomes Translocation, Genetic X Chromosome |
| title | Site-specific X-chromosome rearrangements from hybrid dysgenesis in Drosophila melanogaster |
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