Pregnancy and systemic lupus erythematosus
Eleven patients with 18 pregnancies occurring during the course of systemic lupus erythematosus (SLE) were reviewed. Ten had long-standing lupus glomerulonephritis and a single patient developed glomerulonephritis during pregnancy. Patients were divided into those without (Group A) and those with (G...
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Veröffentlicht in: | American journal of obstetrics and gynecology 1980-10, Vol.138 (4), p.409-413 |
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container_title | American journal of obstetrics and gynecology |
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creator | Houser, Mark T. Fish, Alfred J. Tagatz, George E. Williams, Preston P. Michael, Alfred F. |
description | Eleven patients with 18 pregnancies occurring during the course of systemic lupus erythematosus (SLE) were reviewed. Ten had long-standing lupus glomerulonephritis and a single patient developed glomerulonephritis during pregnancy. Patients were divided into those without (Group A) and those with (Group B) clinical evidence of renal disease or active SLE at conception. In Group A there were 10 pregnancies in five patients; all pregnancies were uncomplicated, except for mild superimposed pre-eclampsia in two, and all resulted in term delivery. Eight pregnancies in six patients occurred in Group B; four pregnancies were complicated by severe (2) or mild (1) superimposed pre-eclampsia and the onset of glomerulonephritis (1), resulting in three premature deliveries and a spontaneous abortion. The remaining four pregnancies were uncomplicated but resulted in one term delivery, one elective abortion, and two spontaneous abortions. None of the patients developed either renal failure or a rapidly progressive course following pregnancy. |
doi_str_mv | 10.1016/0002-9378(80)90138-6 |
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Ten had long-standing lupus glomerulonephritis and a single patient developed glomerulonephritis during pregnancy. Patients were divided into those without (Group A) and those with (Group B) clinical evidence of renal disease or active SLE at conception. In Group A there were 10 pregnancies in five patients; all pregnancies were uncomplicated, except for mild superimposed pre-eclampsia in two, and all resulted in term delivery. Eight pregnancies in six patients occurred in Group B; four pregnancies were complicated by severe (2) or mild (1) superimposed pre-eclampsia and the onset of glomerulonephritis (1), resulting in three premature deliveries and a spontaneous abortion. The remaining four pregnancies were uncomplicated but resulted in one term delivery, one elective abortion, and two spontaneous abortions. None of the patients developed either renal failure or a rapidly progressive course following pregnancy.</description><identifier>ISSN: 0002-9378</identifier><identifier>EISSN: 1097-6868</identifier><identifier>DOI: 10.1016/0002-9378(80)90138-6</identifier><identifier>PMID: 7424997</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Female ; Glomerulonephritis - etiology ; Glomerulonephritis - therapy ; Humans ; Infant, Newborn ; Lupus Erythematosus, Systemic - complications ; Lupus Erythematosus, Systemic - therapy ; Male ; Pregnancy ; Pregnancy Complications - therapy</subject><ispartof>American journal of obstetrics and gynecology, 1980-10, Vol.138 (4), p.409-413</ispartof><rights>1980 The C.V. 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Ten had long-standing lupus glomerulonephritis and a single patient developed glomerulonephritis during pregnancy. Patients were divided into those without (Group A) and those with (Group B) clinical evidence of renal disease or active SLE at conception. In Group A there were 10 pregnancies in five patients; all pregnancies were uncomplicated, except for mild superimposed pre-eclampsia in two, and all resulted in term delivery. Eight pregnancies in six patients occurred in Group B; four pregnancies were complicated by severe (2) or mild (1) superimposed pre-eclampsia and the onset of glomerulonephritis (1), resulting in three premature deliveries and a spontaneous abortion. The remaining four pregnancies were uncomplicated but resulted in one term delivery, one elective abortion, and two spontaneous abortions. None of the patients developed either renal failure or a rapidly progressive course following pregnancy.</description><subject>Adult</subject><subject>Female</subject><subject>Glomerulonephritis - etiology</subject><subject>Glomerulonephritis - therapy</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Lupus Erythematosus, Systemic - complications</subject><subject>Lupus Erythematosus, Systemic - therapy</subject><subject>Male</subject><subject>Pregnancy</subject><subject>Pregnancy Complications - therapy</subject><issn>0002-9378</issn><issn>1097-6868</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1980</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9UMtKxDAUDaKM4-gfKHQlKlSTtEmajSCDLxjQha5DmtxopI8xaYX-va0zzNLV5XAel3MQOiX4mmDCbzDGNJWZKC4KfCkxyYqU76E5wVKkvODFPprvJIfoKMavCVJJZ2gmcppLKebo6jXAR6MbMyS6sUkcYge1N0nVr_uYQBi6T6h118Y-HqMDp6sIJ9u7QO8P92_Lp3T18vi8vFulJmOiS_PMMGF57ggRpSUux5w6oNRQBi5jRVlaqZnj0nHOsC2tEIIKYgGoNCUR2QKdb3LXof3uIXaq9tFAVekG2j4qwajEOWWjMN8ITWhjDODUOvhah0ERrKaJ1FRYTf1VgdXfRIqPtrNtfl_WYHem7SYjf7vhYSz54yGoaDw0BqwPYDplW___g19UxXTs</recordid><startdate>19801015</startdate><enddate>19801015</enddate><creator>Houser, Mark T.</creator><creator>Fish, Alfred J.</creator><creator>Tagatz, George E.</creator><creator>Williams, Preston P.</creator><creator>Michael, Alfred F.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19801015</creationdate><title>Pregnancy and systemic lupus erythematosus</title><author>Houser, Mark T. ; Fish, Alfred J. ; Tagatz, George E. ; Williams, Preston P. ; Michael, Alfred F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-43c57d64f117bd1f4062fe22c25ef358bbd9a5f69f6650dbd777271dee29cb173</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1980</creationdate><topic>Adult</topic><topic>Female</topic><topic>Glomerulonephritis - etiology</topic><topic>Glomerulonephritis - therapy</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Lupus Erythematosus, Systemic - complications</topic><topic>Lupus Erythematosus, Systemic - therapy</topic><topic>Male</topic><topic>Pregnancy</topic><topic>Pregnancy Complications - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Houser, Mark T.</creatorcontrib><creatorcontrib>Fish, Alfred J.</creatorcontrib><creatorcontrib>Tagatz, George E.</creatorcontrib><creatorcontrib>Williams, Preston P.</creatorcontrib><creatorcontrib>Michael, Alfred F.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of obstetrics and gynecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Houser, Mark T.</au><au>Fish, Alfred J.</au><au>Tagatz, George E.</au><au>Williams, Preston P.</au><au>Michael, Alfred F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pregnancy and systemic lupus erythematosus</atitle><jtitle>American journal of obstetrics and gynecology</jtitle><addtitle>Am J Obstet Gynecol</addtitle><date>1980-10-15</date><risdate>1980</risdate><volume>138</volume><issue>4</issue><spage>409</spage><epage>413</epage><pages>409-413</pages><issn>0002-9378</issn><eissn>1097-6868</eissn><abstract>Eleven patients with 18 pregnancies occurring during the course of systemic lupus erythematosus (SLE) were reviewed. Ten had long-standing lupus glomerulonephritis and a single patient developed glomerulonephritis during pregnancy. Patients were divided into those without (Group A) and those with (Group B) clinical evidence of renal disease or active SLE at conception. In Group A there were 10 pregnancies in five patients; all pregnancies were uncomplicated, except for mild superimposed pre-eclampsia in two, and all resulted in term delivery. Eight pregnancies in six patients occurred in Group B; four pregnancies were complicated by severe (2) or mild (1) superimposed pre-eclampsia and the onset of glomerulonephritis (1), resulting in three premature deliveries and a spontaneous abortion. The remaining four pregnancies were uncomplicated but resulted in one term delivery, one elective abortion, and two spontaneous abortions. None of the patients developed either renal failure or a rapidly progressive course following pregnancy.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>7424997</pmid><doi>10.1016/0002-9378(80)90138-6</doi><tpages>5</tpages></addata></record> |
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issn | 0002-9378 1097-6868 |
language | eng |
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source | Elsevier ScienceDirect Journals Complete - AutoHoldings; MEDLINE |
subjects | Adult Female Glomerulonephritis - etiology Glomerulonephritis - therapy Humans Infant, Newborn Lupus Erythematosus, Systemic - complications Lupus Erythematosus, Systemic - therapy Male Pregnancy Pregnancy Complications - therapy |
title | Pregnancy and systemic lupus erythematosus |
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