Pregnancy and systemic lupus erythematosus

Eleven patients with 18 pregnancies occurring during the course of systemic lupus erythematosus (SLE) were reviewed. Ten had long-standing lupus glomerulonephritis and a single patient developed glomerulonephritis during pregnancy. Patients were divided into those without (Group A) and those with (G...

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Veröffentlicht in:American journal of obstetrics and gynecology 1980-10, Vol.138 (4), p.409-413
Hauptverfasser: Houser, Mark T., Fish, Alfred J., Tagatz, George E., Williams, Preston P., Michael, Alfred F.
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container_end_page 413
container_issue 4
container_start_page 409
container_title American journal of obstetrics and gynecology
container_volume 138
creator Houser, Mark T.
Fish, Alfred J.
Tagatz, George E.
Williams, Preston P.
Michael, Alfred F.
description Eleven patients with 18 pregnancies occurring during the course of systemic lupus erythematosus (SLE) were reviewed. Ten had long-standing lupus glomerulonephritis and a single patient developed glomerulonephritis during pregnancy. Patients were divided into those without (Group A) and those with (Group B) clinical evidence of renal disease or active SLE at conception. In Group A there were 10 pregnancies in five patients; all pregnancies were uncomplicated, except for mild superimposed pre-eclampsia in two, and all resulted in term delivery. Eight pregnancies in six patients occurred in Group B; four pregnancies were complicated by severe (2) or mild (1) superimposed pre-eclampsia and the onset of glomerulonephritis (1), resulting in three premature deliveries and a spontaneous abortion. The remaining four pregnancies were uncomplicated but resulted in one term delivery, one elective abortion, and two spontaneous abortions. None of the patients developed either renal failure or a rapidly progressive course following pregnancy.
doi_str_mv 10.1016/0002-9378(80)90138-6
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source Elsevier ScienceDirect Journals Complete - AutoHoldings; MEDLINE
subjects Adult
Female
Glomerulonephritis - etiology
Glomerulonephritis - therapy
Humans
Infant, Newborn
Lupus Erythematosus, Systemic - complications
Lupus Erythematosus, Systemic - therapy
Male
Pregnancy
Pregnancy Complications - therapy
title Pregnancy and systemic lupus erythematosus
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