Pharmacokinetics of atenolol in hypertensive subjects with and without co-administration of chlorthalidone

The pharmacokinetics of atenolol with and without the co-administration of chlorthalidone were studied in five hypertensive subjects. Concomitant administration of chlorthalidone appears to have little if any effect on the pharmacokinetics of atenolol during treatment for 7 days. The atenolol elimin...

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Veröffentlicht in:	European journal of clinical pharmacology 1980-05, Vol.17 (5), p.333-337
Hauptverfasser:	Riva, E, Farina, P L, Sega, R, Tognoni, G, Bastain, W, McAinsh, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Atenolol - administration & dosage Atenolol - metabolism Chlorthalidone - administration & dosage Chlorthalidone - metabolism Drug Therapy, Combination Half-Life Humans Hypertension - blood Hypertension - drug therapy Hypertension - urine Male Propanolamines - metabolism
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