Stability of Packaged Solid Dosage Forms. II. Shelf-life Prediction for Packaged Sugar-coated Tablets Liable to Moisture and Heat Damage

Shelf-life prediction for solid dosage forms that are affected by the moisture content and ambient temperature was investigated in moisture-semipermeable packages. In this study, the color change of a sugar-coated tablet containing ascorbic acid in the core was examined. The kinetics of the color ch...

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Veröffentlicht in:	Chemical & pharmaceutical bulletin 1980/04/25, Vol.28(4), pp.1099-1106
Hauptverfasser:	NAKABAYASHI, KIYOSHI, SHIMAMOTO, TSUGIO, MIMA, HIROYUKI
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption Color Drug Packaging Drug Stability Hot Temperature relative humidity Tablets Technology, Pharmaceutical Water
Online-Zugang:	Volltext
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