Mechanism of action of polymeric aurintricarboxylic acid, a potent inhibitor of protein-nucleic acid interactions

The mechanism of inhibition of protein--nucleic acid complex formation by polymeric aurintricarboxylic acid (ATA) was investigated by proton magnetic resonance spectroscopy. The approach was the synthesis of totally deuterated ATA, followed by a 100-MHz proton magnetic resonance study of its interac...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biochemistry (Easton) 1980-09, Vol.19 (18), p.4299-4303
Hauptverfasser:	Gonzalez, R. Gilberto, Haxo, Robert S, Schleich, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aurintricarboxylic Acid - pharmacology Binding Sites Cattle Cyclohexanecarboxylic Acids - pharmacology Histidine Hydrogen-Ion Concentration Kinetics Magnetic Resonance Spectroscopy Pancreas - enzymology Polymers - pharmacology Protein Binding Protein Conformation Ribonucleases - metabolism RNA
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!