Influence of Enteramine (5 Hydroxytryptamine) on Renal Function of the Dog
Summary 1. Enteramine (5 hydroxy-tryptamine) decreases the urine volume of hydrated dogs at doses which do not stimulate the smooth muscle and do not modify the systemic blood pressure. The lower doses (0, 1-0, 3 mg per kilo) subcutaneously or intravenously decrease the urine volume without affectin...
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| Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1953-04, Vol.82 (4), p.621-623 |
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| container_title | Experimental biology and medicine (Maywood, N.J.) |
| container_volume | 82 |
| creator | Sala, G. Castegnaro, E. |
| description | Summary
1. Enteramine (5 hydroxy-tryptamine) decreases the urine volume of hydrated dogs at doses which do not stimulate the smooth muscle and do not modify the systemic blood pressure. The lower doses (0, 1-0, 3 mg per kilo) subcutaneously or intravenously decrease the urine volume without affecting the GFR, while higher doses reduce also the filtration rate; both lower and higher doses increase the RPF. 2. The above described experiments suggest that the antidiuretic effect of enteramine in the dog derives principally from an increased reabsorption of water from the renal tubule. |
| doi_str_mv | 10.3181/00379727-82-20196 |
| format | Article |
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1. Enteramine (5 hydroxy-tryptamine) decreases the urine volume of hydrated dogs at doses which do not stimulate the smooth muscle and do not modify the systemic blood pressure. The lower doses (0, 1-0, 3 mg per kilo) subcutaneously or intravenously decrease the urine volume without affecting the GFR, while higher doses reduce also the filtration rate; both lower and higher doses increase the RPF. 2. The above described experiments suggest that the antidiuretic effect of enteramine in the dog derives principally from an increased reabsorption of water from the renal tubule.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-82-20196</identifier><identifier>PMID: 13055950</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Animals ; Dogs ; Kidney - drug effects ; Leadership ; Old Medline ; Serotonin ; Serotonin Agents ; Urinary Tract Physiological Phenomena</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1953-04, Vol.82 (4), p.621-623</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c338t-4b09f29d8d4483401b69c5728d26f9b3c8c6538e05dbf46fff838c7f5603110a3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/13055950$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sala, G.</creatorcontrib><creatorcontrib>Castegnaro, E.</creatorcontrib><title>Influence of Enteramine (5 Hydroxytryptamine) on Renal Function of the Dog</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Summary
1. Enteramine (5 hydroxy-tryptamine) decreases the urine volume of hydrated dogs at doses which do not stimulate the smooth muscle and do not modify the systemic blood pressure. The lower doses (0, 1-0, 3 mg per kilo) subcutaneously or intravenously decrease the urine volume without affecting the GFR, while higher doses reduce also the filtration rate; both lower and higher doses increase the RPF. 2. The above described experiments suggest that the antidiuretic effect of enteramine in the dog derives principally from an increased reabsorption of water from the renal tubule.</description><subject>Animals</subject><subject>Dogs</subject><subject>Kidney - drug effects</subject><subject>Leadership</subject><subject>Old Medline</subject><subject>Serotonin</subject><subject>Serotonin Agents</subject><subject>Urinary Tract Physiological Phenomena</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1953</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kF1LwzAUhoMobk5_gDeSK9GLznw0aXIpc3OTgSB6Hdo0mR1dMpMW7L-3-xDvvDrk5HlfDg8A1xiNKRb4ASGayYxkiSAJQVjyEzDEjLKEcilPwXD3n-yAAbiIcY0QZhnh52CAKWJMMjQELwtn69Y4baC3cOoaE_JN5Qy8Y3DelcF_d03ots1-eQ-9g2_G5TWctU43Vf_sU82ngU9-dQnObF5Hc3WcI_Axm75P5sny9XkxeVwmmlLRJGmBpCWyFGWaCpoiXHCp-7tESbiVBdVCc0aFQawsbMqttYIKnVnGEcUY5XQEbg-92-C_WhMbtamiNnWdO-PbqDJGOCYo60F8AHXwMQZj1TZUmzx0CiO1E6h-BSpB1F5gn7k5lrfFxpR_iaOxHhgfgJivjFr7NvQ64j-NP24Ldxs</recordid><startdate>195304</startdate><enddate>195304</enddate><creator>Sala, G.</creator><creator>Castegnaro, E.</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>195304</creationdate><title>Influence of Enteramine (5 Hydroxytryptamine) on Renal Function of the Dog</title><author>Sala, G. ; Castegnaro, E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c338t-4b09f29d8d4483401b69c5728d26f9b3c8c6538e05dbf46fff838c7f5603110a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1953</creationdate><topic>Animals</topic><topic>Dogs</topic><topic>Kidney - drug effects</topic><topic>Leadership</topic><topic>Old Medline</topic><topic>Serotonin</topic><topic>Serotonin Agents</topic><topic>Urinary Tract Physiological Phenomena</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sala, G.</creatorcontrib><creatorcontrib>Castegnaro, E.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sala, G.</au><au>Castegnaro, E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Influence of Enteramine (5 Hydroxytryptamine) on Renal Function of the Dog</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1953-04</date><risdate>1953</risdate><volume>82</volume><issue>4</issue><spage>621</spage><epage>623</epage><pages>621-623</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Summary
1. Enteramine (5 hydroxy-tryptamine) decreases the urine volume of hydrated dogs at doses which do not stimulate the smooth muscle and do not modify the systemic blood pressure. The lower doses (0, 1-0, 3 mg per kilo) subcutaneously or intravenously decrease the urine volume without affecting the GFR, while higher doses reduce also the filtration rate; both lower and higher doses increase the RPF. 2. The above described experiments suggest that the antidiuretic effect of enteramine in the dog derives principally from an increased reabsorption of water from the renal tubule.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>13055950</pmid><doi>10.3181/00379727-82-20196</doi><tpages>3</tpages></addata></record> |
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| ispartof | Experimental biology and medicine (Maywood, N.J.), 1953-04, Vol.82 (4), p.621-623 |
| issn | 0037-9727 1535-3702 1535-3699 |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Animals Dogs Kidney - drug effects Leadership Old Medline Serotonin Serotonin Agents Urinary Tract Physiological Phenomena |
| title | Influence of Enteramine (5 Hydroxytryptamine) on Renal Function of the Dog |
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