Oscillations of IgM antibody affinity at the level of single immunocytes

IgM antibody affinity was measured by hemolytic plaque inhibition assays on spleen cells from mice immunized with a single injection of DNP-dextran. Maturation of affinity was found to occur with time after 1 to 1000 microgram of immunogen and to be characterized by rapid oscillations independent fr...

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Veröffentlicht in:	The Journal of immunology (1950) 1980-09, Vol.125 (3), p.1349-1354
Hauptverfasser:	Pini, C, Di Felice, G, Neri, R, Mancini, C, Vicari, G, Doria, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibody Affinity Antibody Formation Cattle Dinitrobenzenes - immunology gamma-Globulins - immunology Hemolytic Plaque Technique Immunity, Cellular Immunoglobulin M Male Mice Mice, Inbred C3H Spleen - immunology Time Factors Trinitrobenzenes - immunology
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