Essential fatty acid deficiency in patients receiving simultaneous parenteral and oral nutrition

Essential fatty acid deficiency is a common finding in patients nourished parenterally with hypertonic glucose and amino acids. In this study, we measured the Iinoleate concentration in the livers of 3 groups of patients. All the patients had operable upper gastrointestinal tract malignancies. Group...

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Veröffentlicht in:JPEN. Journal of parenteral and enteral nutrition 1980-07, Vol.4 (4), p.343-345
Hauptverfasser: Stein, T. Peter, Buzby, Gordon P, Hargrove, W. Clark III, Leskiw, Maria J, Mullen, James L
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container_start_page 343
container_title JPEN. Journal of parenteral and enteral nutrition
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creator Stein, T. Peter
Buzby, Gordon P
Hargrove, W. Clark III
Leskiw, Maria J
Mullen, James L
description Essential fatty acid deficiency is a common finding in patients nourished parenterally with hypertonic glucose and amino acids. In this study, we measured the Iinoleate concentration in the livers of 3 groups of patients. All the patients had operable upper gastrointestinal tract malignancies. Group I ate the hospital's regular diet ad libitum. Group II were given total parenteral nutrition (TPN). Group III received both enteral and parenteral nutrition and obtained about 35% of their caloric intake from food. The percentage of total liver fatty acids as linoleate were group I, 15.2 ± 1.2%, group II, 3.7 ± 1.4%, and group III, 2.8 ± 1.6%. Data are expressed as the mean ± 1 SEM. The patients who received 35% of their calories by mouth as food and the patients on TPN were found to be equally depleted in linoleate.
doi_str_mv 10.1177/014860718000400401
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source MEDLINE; Wiley Journals; Alma/SFX Local Collection
subjects Aged
Enteral Nutrition - standards
Fatty Acids - metabolism
Fatty Acids, Essential - deficiency
Fatty Liver - metabolism
Gastrointestinal Neoplasms - surgery
Humans
Linoleic Acids - metabolism
Liver - metabolism
Male
Middle Aged
Nutritional Requirements
Parenteral Nutrition - standards
Parenteral Nutrition, Total - standards
title Essential fatty acid deficiency in patients receiving simultaneous parenteral and oral nutrition
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