Tyrosine turnover and protein synthesis during parenteral nutrition
Three patients receiving total parenteral nutrition and one healthy subject receiving 5% glucose were infused for 10 hours with L-(U14C)tyrosine (1.5 microCi/hr). Two alternative assumptions were made regarding the fate of labeled carbon. Total and oxidative fluxes of tyrosine were calculated and th...
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| Veröffentlicht in: | JPEN. Journal of parenteral and enteral nutrition 1980-05, Vol.4 (3), p.261-263 |
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| container_title | JPEN. Journal of parenteral and enteral nutrition |
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| creator | Wells, F E Smits, B J |
| description | Three patients receiving total parenteral nutrition and one healthy subject receiving 5% glucose were infused for 10 hours with L-(U14C)tyrosine (1.5 microCi/hr). Two alternative assumptions were made regarding the fate of labeled carbon. Total and oxidative fluxes of tyrosine were calculated and these were used to determine rates of protein synthesis and breakdown. Patients showed positive net protein synthesis and oxidation of infused phenylalanine via tyrosine was shown not to be excessive. |
| doi_str_mv | 10.1177/0148607180004003261 |
| format | Article |
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Two alternative assumptions were made regarding the fate of labeled carbon. Total and oxidative fluxes of tyrosine were calculated and these were used to determine rates of protein synthesis and breakdown. Patients showed positive net protein synthesis and oxidation of infused phenylalanine via tyrosine was shown not to be excessive.</description><identifier>ISSN: 0148-6071</identifier><identifier>DOI: 10.1177/0148607180004003261</identifier><identifier>PMID: 6772805</identifier><language>eng</language><publisher>United States</publisher><subject>Adult ; Aged ; Crohn Disease - therapy ; Female ; Humans ; Male ; Middle Aged ; Parenteral Nutrition ; Parenteral Nutrition, Total ; Protein Biosynthesis ; Pyloric Stenosis - therapy ; Tyrosine - metabolism</subject><ispartof>JPEN. 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Two alternative assumptions were made regarding the fate of labeled carbon. Total and oxidative fluxes of tyrosine were calculated and these were used to determine rates of protein synthesis and breakdown. Patients showed positive net protein synthesis and oxidation of infused phenylalanine via tyrosine was shown not to be excessive.</description><subject>Adult</subject><subject>Aged</subject><subject>Crohn Disease - therapy</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Parenteral Nutrition</subject><subject>Parenteral Nutrition, Total</subject><subject>Protein Biosynthesis</subject><subject>Pyloric Stenosis - therapy</subject><subject>Tyrosine - metabolism</subject><issn>0148-6071</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1980</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkEtPwzAQhH0AlVL4BQjJJ26BdRw_ckQVL6kSl9wjx1mDUeoU20HqvydVK06cVpqdGe1-hNwwuGdMqQdglZagmAaACoCXkp2R5UEtDvIFuUzpa95xCbAgC6lUqUEsybrZxzH5gDRPMYw_GKkJPd3FMaMPNO1D_sTkE-2n6MMH3ZmIIWM0Aw1Tjj77MVyRc2eGhNenuSLN81Ozfi027y9v68dNYZkuc-GEw8oy4ZhxlZGslq4E0FzIvkPHa2br2vRcca6dgFpYBbaTunOWO8N6viJ3x9r5uO8JU263PlkcBhNwnFKrRAm1Vmo28qPRzq-liK7dRb81cd8yaA-02n9ozanbU_3UbbH_y5xQ8V-4gWgU</recordid><startdate>198005</startdate><enddate>198005</enddate><creator>Wells, F E</creator><creator>Smits, B J</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198005</creationdate><title>Tyrosine turnover and protein synthesis during parenteral nutrition</title><author>Wells, F E ; Smits, B J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c182t-f5fe4c15f1af4a6196f2008356dbef391c99ad37338f5095c70cb68bfc3fa1d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1980</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Crohn Disease - therapy</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Parenteral Nutrition</topic><topic>Parenteral Nutrition, Total</topic><topic>Protein Biosynthesis</topic><topic>Pyloric Stenosis - therapy</topic><topic>Tyrosine - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wells, F E</creatorcontrib><creatorcontrib>Smits, B J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>JPEN. Journal of parenteral and enteral nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wells, F E</au><au>Smits, B J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Tyrosine turnover and protein synthesis during parenteral nutrition</atitle><jtitle>JPEN. Journal of parenteral and enteral nutrition</jtitle><addtitle>JPEN J Parenter Enteral Nutr</addtitle><date>1980-05</date><risdate>1980</risdate><volume>4</volume><issue>3</issue><spage>261</spage><epage>263</epage><pages>261-263</pages><issn>0148-6071</issn><abstract>Three patients receiving total parenteral nutrition and one healthy subject receiving 5% glucose were infused for 10 hours with L-(U14C)tyrosine (1.5 microCi/hr). Two alternative assumptions were made regarding the fate of labeled carbon. Total and oxidative fluxes of tyrosine were calculated and these were used to determine rates of protein synthesis and breakdown. Patients showed positive net protein synthesis and oxidation of infused phenylalanine via tyrosine was shown not to be excessive.</abstract><cop>United States</cop><pmid>6772805</pmid><doi>10.1177/0148607180004003261</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0148-6071 |
| ispartof | JPEN. Journal of parenteral and enteral nutrition, 1980-05, Vol.4 (3), p.261-263 |
| issn | 0148-6071 |
| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete; Alma/SFX Local Collection |
| subjects | Adult Aged Crohn Disease - therapy Female Humans Male Middle Aged Parenteral Nutrition Parenteral Nutrition, Total Protein Biosynthesis Pyloric Stenosis - therapy Tyrosine - metabolism |
| title | Tyrosine turnover and protein synthesis during parenteral nutrition |
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