Identification of an interferon in murine placentas
It is becoming increasingly apparent that interferon exerts a major role in cellular regulatory processes. Besides its well known antiviral properties 1 , interferon has been shown to affect cell surface antigen expression 2,3 , lymphoid cell function 4,5 , as well as cellular protein synthesis 6,7...
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| Veröffentlicht in: | Nature (London) 1980-07, Vol.286 (5770), p.266-267 |
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| creator | Fowler, Arnold K. Reed, Carl D. Giron, David J. |
| description | It is becoming increasingly apparent that interferon exerts a major role in cellular regulatory processes. Besides its well known antiviral properties
1
, interferon has been shown to affect cell surface antigen expression
2,3
, lymphoid cell function
4,5
, as well as cellular protein synthesis
6,7
and growth
8–11
. To date, however, there is little information available on the mechanism of interferon production
in vivo
except in response to a variety of exogenously administered viral and nonviral systemic inducers. We report here the detection of a pregnancy-associated elevation of interferon, or an interferon-like component, in selected reproductive tissues of mice. |
| doi_str_mv | 10.1038/286266a0 |
| format | Article |
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1
, interferon has been shown to affect cell surface antigen expression
2,3
, lymphoid cell function
4,5
, as well as cellular protein synthesis
6,7
and growth
8–11
. To date, however, there is little information available on the mechanism of interferon production
in vivo
except in response to a variety of exogenously administered viral and nonviral systemic inducers. We report here the detection of a pregnancy-associated elevation of interferon, or an interferon-like component, in selected reproductive tissues of mice.</description><identifier>ISSN: 0028-0836</identifier><identifier>EISSN: 1476-4687</identifier><identifier>DOI: 10.1038/286266a0</identifier><identifier>PMID: 6157101</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Animals ; Female ; Fetus - analysis ; Fetus - metabolism ; Gestational Age ; Humanities and Social Sciences ; Interferons - biosynthesis ; Interferons - isolation & purification ; letter ; Mice ; multidisciplinary ; Placenta - analysis ; Placenta - metabolism ; Pregnancy ; Science ; Science (multidisciplinary) ; Uterus - analysis ; Uterus - metabolism</subject><ispartof>Nature (London), 1980-07, Vol.286 (5770), p.266-267</ispartof><rights>Springer Nature Limited 1980</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c312t-66544cfe0e444a72e0686878c249ce9c0e0b2ac6900e5742fae3b41420f25f53</citedby><cites>FETCH-LOGICAL-c312t-66544cfe0e444a72e0686878c249ce9c0e0b2ac6900e5742fae3b41420f25f53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/286266a0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/286266a0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6157101$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fowler, Arnold K.</creatorcontrib><creatorcontrib>Reed, Carl D.</creatorcontrib><creatorcontrib>Giron, David J.</creatorcontrib><title>Identification of an interferon in murine placentas</title><title>Nature (London)</title><addtitle>Nature</addtitle><addtitle>Nature</addtitle><description>It is becoming increasingly apparent that interferon exerts a major role in cellular regulatory processes. Besides its well known antiviral properties
1
, interferon has been shown to affect cell surface antigen expression
2,3
, lymphoid cell function
4,5
, as well as cellular protein synthesis
6,7
and growth
8–11
. To date, however, there is little information available on the mechanism of interferon production
in vivo
except in response to a variety of exogenously administered viral and nonviral systemic inducers. We report here the detection of a pregnancy-associated elevation of interferon, or an interferon-like component, in selected reproductive tissues of mice.</description><subject>Animals</subject><subject>Female</subject><subject>Fetus - analysis</subject><subject>Fetus - metabolism</subject><subject>Gestational Age</subject><subject>Humanities and Social Sciences</subject><subject>Interferons - biosynthesis</subject><subject>Interferons - isolation & purification</subject><subject>letter</subject><subject>Mice</subject><subject>multidisciplinary</subject><subject>Placenta - analysis</subject><subject>Placenta - metabolism</subject><subject>Pregnancy</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Uterus - analysis</subject><subject>Uterus - metabolism</subject><issn>0028-0836</issn><issn>1476-4687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1980</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkE1LAzEQhoMotVbBPyDsSfSwOsnmq0cpfhQKXnoPaTqRLbtJTXYP_nsjrV48zcD78DLzEHJN4YFCox-ZlkxKCydkSrmSNZdanZIpANM16Eaek4ucdwAgqOITMpFUKAp0SprlFsPQ-tbZoY2hir6yoWrDgMljij9r1Y-pDVjtO-sKa_MlOfO2y3h1nDOyfnleL97q1fvrcvG0ql1D2VBLKTh3HgE551YxBKnLWdoxPnc4d4CwYdbJOQAKxZm32Gw45Qw8E140M3J7qN2n-DliHkzfZoddZwPGMRslGEiueQHvDqBLMeeE3uxT29v0ZSiYHz3mV09Bb46d46bH7R949FHy-0OeSxI-MJldHFMoX_7v-gaUbWr7</recordid><startdate>19800717</startdate><enddate>19800717</enddate><creator>Fowler, Arnold K.</creator><creator>Reed, Carl D.</creator><creator>Giron, David J.</creator><general>Nature Publishing Group UK</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19800717</creationdate><title>Identification of an interferon in murine placentas</title><author>Fowler, Arnold K. ; Reed, Carl D. ; Giron, David J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c312t-66544cfe0e444a72e0686878c249ce9c0e0b2ac6900e5742fae3b41420f25f53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1980</creationdate><topic>Animals</topic><topic>Female</topic><topic>Fetus - analysis</topic><topic>Fetus - metabolism</topic><topic>Gestational Age</topic><topic>Humanities and Social Sciences</topic><topic>Interferons - biosynthesis</topic><topic>Interferons - isolation & purification</topic><topic>letter</topic><topic>Mice</topic><topic>multidisciplinary</topic><topic>Placenta - analysis</topic><topic>Placenta - metabolism</topic><topic>Pregnancy</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><topic>Uterus - analysis</topic><topic>Uterus - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fowler, Arnold K.</creatorcontrib><creatorcontrib>Reed, Carl D.</creatorcontrib><creatorcontrib>Giron, David J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Nature (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fowler, Arnold K.</au><au>Reed, Carl D.</au><au>Giron, David J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Identification of an interferon in murine placentas</atitle><jtitle>Nature (London)</jtitle><stitle>Nature</stitle><addtitle>Nature</addtitle><date>1980-07-17</date><risdate>1980</risdate><volume>286</volume><issue>5770</issue><spage>266</spage><epage>267</epage><pages>266-267</pages><issn>0028-0836</issn><eissn>1476-4687</eissn><abstract>It is becoming increasingly apparent that interferon exerts a major role in cellular regulatory processes. Besides its well known antiviral properties
1
, interferon has been shown to affect cell surface antigen expression
2,3
, lymphoid cell function
4,5
, as well as cellular protein synthesis
6,7
and growth
8–11
. To date, however, there is little information available on the mechanism of interferon production
in vivo
except in response to a variety of exogenously administered viral and nonviral systemic inducers. We report here the detection of a pregnancy-associated elevation of interferon, or an interferon-like component, in selected reproductive tissues of mice.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>6157101</pmid><doi>10.1038/286266a0</doi><tpages>2</tpages></addata></record> |
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| ispartof | Nature (London), 1980-07, Vol.286 (5770), p.266-267 |
| issn | 0028-0836 1476-4687 |
| language | eng |
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| source | MEDLINE; Nature; SpringerLink Journals - AutoHoldings |
| subjects | Animals Female Fetus - analysis Fetus - metabolism Gestational Age Humanities and Social Sciences Interferons - biosynthesis Interferons - isolation & purification letter Mice multidisciplinary Placenta - analysis Placenta - metabolism Pregnancy Science Science (multidisciplinary) Uterus - analysis Uterus - metabolism |
| title | Identification of an interferon in murine placentas |
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