Enhancement of phagocytosis — A newly found activity of Substance P residing in its N-terminal tetrapeptide sequence

The undecapeptide Substance P stimulates phagocytosis by mouse macrophages and human polymorphonuclear leukocytes. The activity of Substance P resides in its N-terminal tetrapeptide protion. Substance P and its N-terminal tetrapeptide are as active as tuftsin in their phagocytosis-stimulating activi...

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Veröffentlicht in:	Biochemical and biophysical research communications 1980-06, Vol.94 (4), p.1445-1451
Hauptverfasser:	Bar-Shavit, Z., Goldman, R., Stabinsky, Y., Gottlieb, P., Fridkin, M., Teichberg, V.I., Blumberg, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Humans Kinetics Macrophages - drug effects Macrophages - physiology Mice Mice, Inbred BALB C Neutrophils - drug effects Neutrophils - physiology Peptide Fragments - pharmacology Phagocytosis - drug effects Receptors, Immunologic - metabolism Substance P - pharmacology Tuftsin - metabolism
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