CT of noncystic liver lesions: bolus enhancement
The combination of rapid bolus injections of urographic contrast medium and timed sequential computed tomography (CT) scans permits recognition of different patterns of enhancement. In a series of 68 proven tumors of the liver, minimal enhancement was observed in 68% of the lesions, homogeneous posi...
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Veröffentlicht in: | American journal of roentgenology (1976) 1980-07, Vol.135 (1), p.57-65 |
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container_title | American journal of roentgenology (1976) |
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creator | Marchal, GJ Baert, AL Wilms, GE |
description | The combination of rapid bolus injections of urographic contrast medium and timed sequential computed tomography (CT) scans permits recognition of different patterns of enhancement. In a series of 68 proven tumors of the liver, minimal enhancement was observed in 68% of the lesions, homogeneous positive enhancement in 9%, and complex patterns in 23%. Sequential scanning of these lesions demonstrated both early and late contrast enhancement. Early enhancement seems to be related to tumor vascularity, whereas delayed uptake may be caused by slow diffusion into an abnormally large extravascular space. Although the combination of bolus injection and serial scans seems very promising in the detection of solid liver tumors, the usefulness of the method is limited by present inability to study the entire organ sequentially. |
doi_str_mv | 10.2214/ajr.135.1.57 |
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In a series of 68 proven tumors of the liver, minimal enhancement was observed in 68% of the lesions, homogeneous positive enhancement in 9%, and complex patterns in 23%. Sequential scanning of these lesions demonstrated both early and late contrast enhancement. Early enhancement seems to be related to tumor vascularity, whereas delayed uptake may be caused by slow diffusion into an abnormally large extravascular space. Although the combination of bolus injection and serial scans seems very promising in the detection of solid liver tumors, the usefulness of the method is limited by present inability to study the entire organ sequentially.</description><subject>Carcinoma, Hepatocellular - diagnostic imaging</subject><subject>Contrast Media - administration & dosage</subject><subject>Hemangioma - diagnostic imaging</subject><subject>Humans</subject><subject>Injections, Intravenous</subject><subject>Liver Neoplasms - diagnostic imaging</subject><subject>Neoplasm Metastasis</subject><subject>Time Factors</subject><subject>Tomography, X-Ray Computed - methods</subject><issn>0361-803X</issn><issn>1546-3141</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1980</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kDtPwzAURi0EKqWwsSJlgYkE38SPhA1VvKRKLEVisxz7mqbKo9gJVf89Qa06fcN3dIZDyDXQJE2BPei1TyDjCSRcnpApcCbiDBickinNBMQ5zb7OyUUIa0qpzAs5IRORsgJoPiV0vow6F7Vda3ahr0xUV7_ooxpD1bXhMSq7eggRtivdGmyw7S_JmdN1wKvDzsjny_Ny_hYvPl7f50-L2KQZ9LFxTthSpAUW3ArmZJGnVGQAJsWitGVujXECmbbCMiGdlpwZjVRalJBLm83I3d678d3PgKFXTRUM1rVusRuCkhxkIXg-gvd70PguBI9ObXzVaL9TQNV_IDUGUmMgBYrLEb85eIeyQXuED0XG_3b_r6rv1bbyqEKj63qkQW2326PnD310bkU</recordid><startdate>198007</startdate><enddate>198007</enddate><creator>Marchal, GJ</creator><creator>Baert, AL</creator><creator>Wilms, GE</creator><general>Am Roentgen Ray Soc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198007</creationdate><title>CT of noncystic liver lesions: bolus enhancement</title><author>Marchal, GJ ; Baert, AL ; Wilms, GE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c231t-cff6db629e95d64f798206311c2e9bdb8dccf6e4ad6d467fa754cae07de7187d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1980</creationdate><topic>Carcinoma, Hepatocellular - diagnostic imaging</topic><topic>Contrast Media - administration & dosage</topic><topic>Hemangioma - diagnostic imaging</topic><topic>Humans</topic><topic>Injections, Intravenous</topic><topic>Liver Neoplasms - diagnostic imaging</topic><topic>Neoplasm Metastasis</topic><topic>Time Factors</topic><topic>Tomography, X-Ray Computed - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Marchal, GJ</creatorcontrib><creatorcontrib>Baert, AL</creatorcontrib><creatorcontrib>Wilms, GE</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of roentgenology (1976)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Marchal, GJ</au><au>Baert, AL</au><au>Wilms, GE</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>CT of noncystic liver lesions: bolus enhancement</atitle><jtitle>American journal of roentgenology (1976)</jtitle><addtitle>AJR Am J Roentgenol</addtitle><date>1980-07</date><risdate>1980</risdate><volume>135</volume><issue>1</issue><spage>57</spage><epage>65</epage><pages>57-65</pages><issn>0361-803X</issn><eissn>1546-3141</eissn><abstract>The combination of rapid bolus injections of urographic contrast medium and timed sequential computed tomography (CT) scans permits recognition of different patterns of enhancement. 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source | American Roentgen Ray Society; MEDLINE; Alma/SFX Local Collection |
subjects | Carcinoma, Hepatocellular - diagnostic imaging Contrast Media - administration & dosage Hemangioma - diagnostic imaging Humans Injections, Intravenous Liver Neoplasms - diagnostic imaging Neoplasm Metastasis Time Factors Tomography, X-Ray Computed - methods |
title | CT of noncystic liver lesions: bolus enhancement |
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