Acylthioxanthenes: agents which selectively reduce decerebrate rigidity in the cat

A series of 2-acylthioxanthene-delta 9 (gamma)-propylamines was synthesized, and their effect of reducing the intercollicular decerebrate rigidity in the cat was evaluated. The compound exhibiting the greatest separation between the dosage that reduced rigidity and that which caused sedation was (Z)...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of medicinal chemistry 1980-06, Vol.23 (6), p.653-657
Hauptverfasser:	Ashton, Michael J, Chapman, Robert F, Loveless, Anthony H
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Cats Decerebrate State - physiopathology Infusions, Parenteral Isomerism Mice Motor Activity - drug effects Structure-Activity Relationship Thioxanthenes - administration & dosage Thioxanthenes - chemical synthesis Thioxanthenes - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!