COMPARATIVE EFFECTS OF CALCIUM CHLORIDE AND CALCIUM GLUCEPTATE
Calcium chloride and calcium gluceptate were compared in their ability to increase plasma ionized calcium concentrations ([Ca2+]). To correct a low ionized calcium concentration, each of 10 critically ill patients received both calcium chloride (10 ml of a 10% solution, containing elemental calcium...
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| Veröffentlicht in: | British journal of anaesthesia : BJA 1980-05, Vol.52 (5), p.501-505 |
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| container_title | British journal of anaesthesia : BJA |
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| creator | DROP, L.J. CULLEN, D.J. |
| description | Calcium chloride and calcium gluceptate were compared in their ability to increase plasma ionized calcium concentrations ([Ca2+]). To correct a low ionized calcium concentration, each of 10 critically ill patients received both calcium chloride (10 ml of a 10% solution, containing elemental calcium 27 mg ml−1) and calcium gluceptate (20 ml, containing elemental calcium 18 mg ml−1) over a 5-min period in randomized order approximately 6 h apart. [Ca2+] and haemodynamic variables (mean arterial pressure (MAP), mean right atrial pressure (RAP) and heart rate (HR)) were monitored for a 30-min period following completion of calcium infusion. Infusion of either calcium preparation was associated with similar increases in [Ca2+] (5 min after infusion of calcium chloride: 33±3.1%; calcium gluceptate: 32± 4.3% (mean±SEM)) and the effects on MAP were similar for each solution (11.1±1.8% and 9.7 ± 2.4%, respectively). |
| doi_str_mv | 10.1093/bja/52.5.501 |
| format | Article |
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To correct a low ionized calcium concentration, each of 10 critically ill patients received both calcium chloride (10 ml of a 10% solution, containing elemental calcium 27 mg ml−1) and calcium gluceptate (20 ml, containing elemental calcium 18 mg ml−1) over a 5-min period in randomized order approximately 6 h apart. [Ca2+] and haemodynamic variables (mean arterial pressure (MAP), mean right atrial pressure (RAP) and heart rate (HR)) were monitored for a 30-min period following completion of calcium infusion. Infusion of either calcium preparation was associated with similar increases in [Ca2+] (5 min after infusion of calcium chloride: 33±3.1%; calcium gluceptate: 32± 4.3% (mean±SEM)) and the effects on MAP were similar for each solution (11.1±1.8% and 9.7 ± 2.4%, respectively).</description><identifier>ISSN: 0007-0912</identifier><identifier>EISSN: 1471-6771</identifier><identifier>DOI: 10.1093/bja/52.5.501</identifier><identifier>PMID: 7387803</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Adult ; Aged ; Calcium - blood ; Calcium - therapeutic use ; Calcium Chloride - pharmacology ; Calcium Chloride - therapeutic use ; Female ; Fluid Therapy ; Hemodynamics - drug effects ; Humans ; Hypocalcemia - therapy ; Male ; Middle Aged ; Organotechnetium Compounds ; Sugar Acids - therapeutic use</subject><ispartof>British journal of anaesthesia : BJA, 1980-05, Vol.52 (5), p.501-505</ispartof><rights>1980</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c409t-1cca1a880cc04788a3b99ce224d65301eebfc41f2ef3b0e4cbd4dde10802a38b3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7387803$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>DROP, L.J.</creatorcontrib><creatorcontrib>CULLEN, D.J.</creatorcontrib><title>COMPARATIVE EFFECTS OF CALCIUM CHLORIDE AND CALCIUM GLUCEPTATE</title><title>British journal of anaesthesia : BJA</title><addtitle>Br J Anaesth</addtitle><description>Calcium chloride and calcium gluceptate were compared in their ability to increase plasma ionized calcium concentrations ([Ca2+]). To correct a low ionized calcium concentration, each of 10 critically ill patients received both calcium chloride (10 ml of a 10% solution, containing elemental calcium 27 mg ml−1) and calcium gluceptate (20 ml, containing elemental calcium 18 mg ml−1) over a 5-min period in randomized order approximately 6 h apart. [Ca2+] and haemodynamic variables (mean arterial pressure (MAP), mean right atrial pressure (RAP) and heart rate (HR)) were monitored for a 30-min period following completion of calcium infusion. Infusion of either calcium preparation was associated with similar increases in [Ca2+] (5 min after infusion of calcium chloride: 33±3.1%; calcium gluceptate: 32± 4.3% (mean±SEM)) and the effects on MAP were similar for each solution (11.1±1.8% and 9.7 ± 2.4%, respectively).</description><subject>Adult</subject><subject>Aged</subject><subject>Calcium - blood</subject><subject>Calcium - therapeutic use</subject><subject>Calcium Chloride - pharmacology</subject><subject>Calcium Chloride - therapeutic use</subject><subject>Female</subject><subject>Fluid Therapy</subject><subject>Hemodynamics - drug effects</subject><subject>Humans</subject><subject>Hypocalcemia - therapy</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Organotechnetium Compounds</subject><subject>Sugar Acids - therapeutic use</subject><issn>0007-0912</issn><issn>1471-6771</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1980</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkE1Lw0AQhhdRaq3evAo5eTLtbDab3VyEkKYf2NpSUxEvy2YzgWi_zLai_96Ulp48Dcz78M7wEHJLoU0hZJ3sQ3e41-ZtDvSMNKkvqBsIQc9JEwCECyH1LsmVtR8AVHghb5CGYFJIYE3yGE_G02gWpcPXxEl6vSROX5xJz4mjUTycj514MJrMht3EiZ67p2V_NI-TaRqlyTW5KPTC4s1xtsi8l6TxwB1N-sMad40P4dalxmiqpQRjwBdSapaFoUHP8_OAM6CIWWF8WnhYsAzQN1nu5zlSkOBpJjPWIveH3k21_tqh3aplaQ0uFnqF651VglMuOYcafDiAplpbW2GhNlW51NWvoqD2ulStS3FPcVXrqvG7Y-8uW2J-go9-6tw95KXd4s8p1tWnCgQTXA3e3lUYDOIn4FTtzwcHHmsZ3yVWypoSVwbzskKzVfm6_P-RP-VDgMI</recordid><startdate>198005</startdate><enddate>198005</enddate><creator>DROP, L.J.</creator><creator>CULLEN, D.J.</creator><general>Elsevier Ltd</general><general>Oxford University Press</general><scope>6I.</scope><scope>AAFTH</scope><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198005</creationdate><title>COMPARATIVE EFFECTS OF CALCIUM CHLORIDE AND CALCIUM GLUCEPTATE</title><author>DROP, L.J. ; CULLEN, D.J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c409t-1cca1a880cc04788a3b99ce224d65301eebfc41f2ef3b0e4cbd4dde10802a38b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1980</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Calcium - blood</topic><topic>Calcium - therapeutic use</topic><topic>Calcium Chloride - pharmacology</topic><topic>Calcium Chloride - therapeutic use</topic><topic>Female</topic><topic>Fluid Therapy</topic><topic>Hemodynamics - drug effects</topic><topic>Humans</topic><topic>Hypocalcemia - therapy</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Organotechnetium Compounds</topic><topic>Sugar Acids - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>DROP, L.J.</creatorcontrib><creatorcontrib>CULLEN, D.J.</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of anaesthesia : BJA</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>DROP, L.J.</au><au>CULLEN, D.J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>COMPARATIVE EFFECTS OF CALCIUM CHLORIDE AND CALCIUM GLUCEPTATE</atitle><jtitle>British journal of anaesthesia : BJA</jtitle><addtitle>Br J Anaesth</addtitle><date>1980-05</date><risdate>1980</risdate><volume>52</volume><issue>5</issue><spage>501</spage><epage>505</epage><pages>501-505</pages><issn>0007-0912</issn><eissn>1471-6771</eissn><abstract>Calcium chloride and calcium gluceptate were compared in their ability to increase plasma ionized calcium concentrations ([Ca2+]). To correct a low ionized calcium concentration, each of 10 critically ill patients received both calcium chloride (10 ml of a 10% solution, containing elemental calcium 27 mg ml−1) and calcium gluceptate (20 ml, containing elemental calcium 18 mg ml−1) over a 5-min period in randomized order approximately 6 h apart. [Ca2+] and haemodynamic variables (mean arterial pressure (MAP), mean right atrial pressure (RAP) and heart rate (HR)) were monitored for a 30-min period following completion of calcium infusion. Infusion of either calcium preparation was associated with similar increases in [Ca2+] (5 min after infusion of calcium chloride: 33±3.1%; calcium gluceptate: 32± 4.3% (mean±SEM)) and the effects on MAP were similar for each solution (11.1±1.8% and 9.7 ± 2.4%, respectively).</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>7387803</pmid><doi>10.1093/bja/52.5.501</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0007-0912 |
| ispartof | British journal of anaesthesia : BJA, 1980-05, Vol.52 (5), p.501-505 |
| issn | 0007-0912 1471-6771 |
| language | eng |
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| source | MEDLINE; EZB Free E-Journals; Oxford Journals A-Z Collection; Alma/SFX Local Collection |
| subjects | Adult Aged Calcium - blood Calcium - therapeutic use Calcium Chloride - pharmacology Calcium Chloride - therapeutic use Female Fluid Therapy Hemodynamics - drug effects Humans Hypocalcemia - therapy Male Middle Aged Organotechnetium Compounds Sugar Acids - therapeutic use |
| title | COMPARATIVE EFFECTS OF CALCIUM CHLORIDE AND CALCIUM GLUCEPTATE |
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