2-Hydroxylation of estrogens in the brain participates in the initiation of the preovulatory LH surge in the rat

Estradiol-2-hydroxylase, the enzyme responsible for the conversion of estrogens to catechol estrogens was measured in the brain of female rats at specific stages of the estrus cycle. Radiometric measurements of the enzyme activity in microsomal, mitochondrial, and synaptosomal fractions of the brain...

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Veröffentlicht in:	Biochemical and biophysical research communications 1980-03, Vol.93 (2), p.471-477
Hauptverfasser:	Fishman, Jack, Norton, Baiba I., Krey, Lewis
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - enzymology Cytochrome P-450 CYP1A1 Estrogens - metabolism Estrus Female Luteinizing Hormone - metabolism Microsomes - enzymology Mitochondria - enzymology Pregnancy Rats Steroid Hydroxylases - metabolism Synaptosomes - enzymology
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