Steroid transforming enzymes in microorganisms. XIII. Relationship between steroid structure and induction of 4-ene-3-oxosteroid: (acceptor)-1-ene-oxidoreductase in Nocardia opaca
The induction of the 4-ene-3-oxosteroid: (acceptor)-1-ene-oxidoreductase in Nocardia opaca has been shown to be dependent on both hydrophilic and hydrophobic structural features of the steroid molecule, i.g. the nature of the oxygen function in positions 11 and 20 and the presence of the methyl grou...
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| Veröffentlicht in: | Zeitschrift fur allgemeine Mikrobiologie 1980, Vol.20 (1), p.23-32 |
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| creator | Hörhold, C Hüller, E Rose, G |
| description | The induction of the 4-ene-3-oxosteroid: (acceptor)-1-ene-oxidoreductase in Nocardia opaca has been shown to be dependent on both hydrophilic and hydrophobic structural features of the steroid molecule, i.g. the nature of the oxygen function in positions 11 and 20 and the presence of the methyl group in position 10 influence the induction of the enzyme drastically. In this connection the metabolism of the steroid inductors being degradated during the induction process has been considered. |
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XIII. Relationship between steroid structure and induction of 4-ene-3-oxosteroid: (acceptor)-1-ene-oxidoreductase in Nocardia opaca</title><title>Zeitschrift fur allgemeine Mikrobiologie</title><addtitle>Z Allg Mikrobiol</addtitle><description>The induction of the 4-ene-3-oxosteroid: (acceptor)-1-ene-oxidoreductase in Nocardia opaca has been shown to be dependent on both hydrophilic and hydrophobic structural features of the steroid molecule, i.g. the nature of the oxygen function in positions 11 and 20 and the presence of the methyl group in position 10 influence the induction of the enzyme drastically. In this connection the metabolism of the steroid inductors being degradated during the induction process has been considered.</description><subject>Enzyme Induction</subject><subject>Estradiol - analogs & derivatives</subject><subject>Estradiol - metabolism</subject><subject>Nocardia - enzymology</subject><subject>Oxidoreductases - biosynthesis</subject><subject>Pregnanes - metabolism</subject><subject>Structure-Activity Relationship</subject><subject>Testosterone - analogs & derivatives</subject><subject>Testosterone - metabolism</subject><issn>0044-2208</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1980</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNotkMtOwzAQRbMAlVL4BCSvECxSxXGe7FDFI1IFEnTBLhrbk2KU2MF2RMtv8YOkkNVo5p45Gs1RMI-iJAnjOCpOglPnPqKIZUnCZsEsZ3mWFfk8-Hn1aI2SxFvQrjG2U3pLUH_vO3REadIpYY2xW9DKdW5J3qqqWpIXbMEro9276glH_4WoiZtUzttB-MEiAS1Hhxy7kSWmIUmIGkMWmp2Z6BtyBUJg7429DulfbHZKGouHNXB4OOLJCLBSATE9CDgLjhtoHZ5PdRFs7u82q8dw_fxQrW7XYZ-yPJQRZ5iWIssFLwRvgHKJ4yyXRclokzaiLFkTSykznlAueIoFZRFFKJHSGNgiuPzX9tZ8Duh83SknsG1BoxlcnaeUplkcj-DFBA68Q1n3VnVg9_X0ZPYLPRN8kQ</recordid><startdate>1980</startdate><enddate>1980</enddate><creator>Hörhold, C</creator><creator>Hüller, E</creator><creator>Rose, G</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>1980</creationdate><title>Steroid transforming enzymes in microorganisms. 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XIII. Relationship between steroid structure and induction of 4-ene-3-oxosteroid: (acceptor)-1-ene-oxidoreductase in Nocardia opaca</atitle><jtitle>Zeitschrift fur allgemeine Mikrobiologie</jtitle><addtitle>Z Allg Mikrobiol</addtitle><date>1980</date><risdate>1980</risdate><volume>20</volume><issue>1</issue><spage>23</spage><epage>32</epage><pages>23-32</pages><issn>0044-2208</issn><abstract>The induction of the 4-ene-3-oxosteroid: (acceptor)-1-ene-oxidoreductase in Nocardia opaca has been shown to be dependent on both hydrophilic and hydrophobic structural features of the steroid molecule, i.g. the nature of the oxygen function in positions 11 and 20 and the presence of the methyl group in position 10 influence the induction of the enzyme drastically. In this connection the metabolism of the steroid inductors being degradated during the induction process has been considered.</abstract><cop>Germany</cop><pmid>7376687</pmid><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0044-2208 |
| ispartof | Zeitschrift fur allgemeine Mikrobiologie, 1980, Vol.20 (1), p.23-32 |
| issn | 0044-2208 |
| language | ger |
| recordid | cdi_proquest_miscellaneous_75115622 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Enzyme Induction Estradiol - analogs & derivatives Estradiol - metabolism Nocardia - enzymology Oxidoreductases - biosynthesis Pregnanes - metabolism Structure-Activity Relationship Testosterone - analogs & derivatives Testosterone - metabolism |
| title | Steroid transforming enzymes in microorganisms. XIII. Relationship between steroid structure and induction of 4-ene-3-oxosteroid: (acceptor)-1-ene-oxidoreductase in Nocardia opaca |
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