Lymph node invasion and prognosis in nephroblastoma
Five hundred and twelve children with Wilms' tumor Stages I, II, and III registered to the International Society of Pediatric Oncology (SIOP) nephroblastoma trial were analyzed as to the prognostic value of metastatic lymph node involvement. The lymph nodes of 300 patients were submitted for mi...
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| Veröffentlicht in: | Cancer 1980-04, Vol.45 (7), p.1632-1636 |
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| container_issue | 7 |
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| container_title | Cancer |
| container_volume | 45 |
| creator | Jereb, B. Tournade, M. F. Lemerle, J. Voǔte, P. A. Delemarre, J. F. Ahstrom, L. Flamant, R. Gérard‐Marchant, R. Sandstedt, B. |
| description | Five hundred and twelve children with Wilms' tumor Stages I, II, and III registered to the International Society of Pediatric Oncology (SIOP) nephroblastoma trial were analyzed as to the prognostic value of metastatic lymph node involvement. The lymph nodes of 300 patients were submitted for microscopic examination; malignant invasion was reported in 15%. The disease‐free and the actuarial survival rates for patients with metastatic lymph node invasion were significantly worse than for those without metastatic lymph node involvement. Radical lymph node dissection neither improved the cure rate nor decreased the rate of abdominal recurrence in patients with lymph node metastases. |
| doi_str_mv | 10.1002/1097-0142(19800401)45:7<1632::AID-CNCR2820450719>3.0.CO;2-F |
| format | Article |
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F. ; Lemerle, J. ; Voǔte, P. A. ; Delemarre, J. F. ; Ahstrom, L. ; Flamant, R. ; Gérard‐Marchant, R. ; Sandstedt, B.</creator><creatorcontrib>Jereb, B. ; Tournade, M. F. ; Lemerle, J. ; Voǔte, P. A. ; Delemarre, J. F. ; Ahstrom, L. ; Flamant, R. ; Gérard‐Marchant, R. ; Sandstedt, B.</creatorcontrib><description>Five hundred and twelve children with Wilms' tumor Stages I, II, and III registered to the International Society of Pediatric Oncology (SIOP) nephroblastoma trial were analyzed as to the prognostic value of metastatic lymph node involvement. The lymph nodes of 300 patients were submitted for microscopic examination; malignant invasion was reported in 15%. The disease‐free and the actuarial survival rates for patients with metastatic lymph node invasion were significantly worse than for those without metastatic lymph node involvement. Radical lymph node dissection neither improved the cure rate nor decreased the rate of abdominal recurrence in patients with lymph node metastases.</description><identifier>ISSN: 0008-543X</identifier><identifier>EISSN: 1097-0142</identifier><identifier>DOI: 10.1002/1097-0142(19800401)45:7<1632::AID-CNCR2820450719>3.0.CO;2-F</identifier><identifier>PMID: 6245781</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adolescent ; Child ; Child, Preschool ; Humans ; Kidney Neoplasms - diagnosis ; Kidney Neoplasms - mortality ; Kidney Neoplasms - pathology ; Lymph Nodes - pathology ; Lymphatic Metastasis ; Prognosis ; Wilms Tumor - diagnosis ; Wilms Tumor - mortality ; Wilms Tumor - pathology</subject><ispartof>Cancer, 1980-04, Vol.45 (7), p.1632-1636</ispartof><rights>Copyright © 1980 American Cancer Society</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3849-6cbd6bf643144847a7144c9c494497f8f51c5186299a87f74cf6cde2489afeb13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6245781$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jereb, B.</creatorcontrib><creatorcontrib>Tournade, M. 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The disease‐free and the actuarial survival rates for patients with metastatic lymph node invasion were significantly worse than for those without metastatic lymph node involvement. Radical lymph node dissection neither improved the cure rate nor decreased the rate of abdominal recurrence in patients with lymph node metastases.</description><subject>Adolescent</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Humans</subject><subject>Kidney Neoplasms - diagnosis</subject><subject>Kidney Neoplasms - mortality</subject><subject>Kidney Neoplasms - pathology</subject><subject>Lymph Nodes - pathology</subject><subject>Lymphatic Metastasis</subject><subject>Prognosis</subject><subject>Wilms Tumor - diagnosis</subject><subject>Wilms Tumor - mortality</subject><subject>Wilms Tumor - pathology</subject><issn>0008-543X</issn><issn>1097-0142</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1980</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkN-LEzEQx4MoZ63-CcI-iT5snSSTTVJFOFbrHRQLxwmCD0M2m3gr-6Nurkr_e7e0HngPgk_DzHfmOzMfxkoOCw4gXnOwOgeO4iW3BgCBv0K11G95IcVyeX75Pi8_lVfCCEAFmtt3cgGLcvNG5KsHbHY3_ZDNAMDkCuWXx-xJSt-nVAslz9hZIVBpw2dMrvfd9ibrhzpkTf_TpWboM9fX2XYcvvVDatJUzvqwvRmHqnXpdujcU_YoujaFZ6c4Z59XH67Li3y9-XhZnq9zLw3avPBVXVSxQMkRDWqnp-itR4todTRRca-4KYS1zuio0cfC10GgsS6Giss5e3H0nW75sQvplrom-dC2rg_DLpFWYKWd3puzr8dGPw4pjSHSdmw6N-6JAx2Q0gEKHaDQH6SEijQdkBJNSOlvpCQJqNyQoNXk_vx0xq7qQn3nfWI46fGo_2rasP-_1f_cfE-RvwFBTZKh</recordid><startdate>19800401</startdate><enddate>19800401</enddate><creator>Jereb, B.</creator><creator>Tournade, M. 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F. ; Ahstrom, L. ; Flamant, R. ; Gérard‐Marchant, R. ; Sandstedt, B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3849-6cbd6bf643144847a7144c9c494497f8f51c5186299a87f74cf6cde2489afeb13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1980</creationdate><topic>Adolescent</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Humans</topic><topic>Kidney Neoplasms - diagnosis</topic><topic>Kidney Neoplasms - mortality</topic><topic>Kidney Neoplasms - pathology</topic><topic>Lymph Nodes - pathology</topic><topic>Lymphatic Metastasis</topic><topic>Prognosis</topic><topic>Wilms Tumor - diagnosis</topic><topic>Wilms Tumor - mortality</topic><topic>Wilms Tumor - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jereb, B.</creatorcontrib><creatorcontrib>Tournade, M. F.</creatorcontrib><creatorcontrib>Lemerle, J.</creatorcontrib><creatorcontrib>Voǔte, P. A.</creatorcontrib><creatorcontrib>Delemarre, J. F.</creatorcontrib><creatorcontrib>Ahstrom, L.</creatorcontrib><creatorcontrib>Flamant, R.</creatorcontrib><creatorcontrib>Gérard‐Marchant, R.</creatorcontrib><creatorcontrib>Sandstedt, B.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jereb, B.</au><au>Tournade, M. F.</au><au>Lemerle, J.</au><au>Voǔte, P. A.</au><au>Delemarre, J. 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| fulltext | fulltext |
| identifier | ISSN: 0008-543X |
| ispartof | Cancer, 1980-04, Vol.45 (7), p.1632-1636 |
| issn | 0008-543X 1097-0142 |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adolescent Child Child, Preschool Humans Kidney Neoplasms - diagnosis Kidney Neoplasms - mortality Kidney Neoplasms - pathology Lymph Nodes - pathology Lymphatic Metastasis Prognosis Wilms Tumor - diagnosis Wilms Tumor - mortality Wilms Tumor - pathology |
| title | Lymph node invasion and prognosis in nephroblastoma |
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