The use of synchrotron radiation in time-resolved X-ray diffraction studies of myosin layer-line reflections during muscle contraction

Experiments on striated muscle have been carried out at the EMBL Outstation at DESY, Hamburg, using the electron-positron storage ring DORIS as a high-intensity X-ray source. The low-angle reflections from the myosin cross-bridges could be recorded more than 1,000 times more rapidly than with the be...

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Veröffentlicht in:Nature (London) 1980-03, Vol.284 (5752), p.140-143
Hauptverfasser: Huxley, H. E, Faruqi, A. R, Bordas, J, Koch, M. H. J, Milch, J. R
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container_end_page 143
container_issue 5752
container_start_page 140
container_title Nature (London)
container_volume 284
creator Huxley, H. E
Faruqi, A. R
Bordas, J
Koch, M. H. J
Milch, J. R
description Experiments on striated muscle have been carried out at the EMBL Outstation at DESY, Hamburg, using the electron-positron storage ring DORIS as a high-intensity X-ray source. The low-angle reflections from the myosin cross-bridges could be recorded more than 1,000 times more rapidly than with the best conventional X-ray sources, and could be followed during contraction with a time resolution of 10 ms.
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subjects Animals
Anura
Cytoskeleton - physiology
Cytoskeleton - ultrastructure
Muscle Contraction
Muscles - ultrastructure
Myosins
Particle Accelerators
X-Ray Diffraction - instrumentation
title The use of synchrotron radiation in time-resolved X-ray diffraction studies of myosin layer-line reflections during muscle contraction
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