Stimulation by Bradykinin of Afferent Vagal C-Fibers with Chemosensitive Endings in the Heart and Aorta of the Dog

Bradykinin applied directly to the epicardium evokes a reflex increase in blood pressure by stimulating sympathetic afferent nerve endings in the heart, but injected into the coronary artery it evokes vagally mediated reflex decreases in heart rate and blood pressure. The afferents initiating these...

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Veröffentlicht in:	Circulation research 1980-04, Vol.46 (4), p.476-484
Hauptverfasser:	KAUFMAN, MARC P, BAKER, DAVID G, COLERIDGE, HAZEL M, COLERIDGE, JOHN C.G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta - drug effects Aortic Bodies - drug effects Blood Pressure - drug effects Bradykinin - pharmacology Capsaicin - pharmacology Chemoreceptor Cells - drug effects Dogs Heart - drug effects Heart Rate - drug effects Mechanoreceptors - drug effects Nerve Endings - drug effects Nerve Fibers - drug effects Pressoreceptors - drug effects Vagus Nerve - drug effects
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