INFLUENZA A/USSR/77 (H1N1) ON A UNIVERSITY CAMPUS
An extensive outbreak of influenza caused by A/USSR/77 (H1N1) virus occurred in February, 1978, at the University of Maryland, College Park, Maryland, and the outbreak was studied by virus isolation, serology, clinical questionnaire and outpatient chart review. Among students who returned questionna...
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Veröffentlicht in: | American journal of epidemiology 1980-01, Vol.111 (1), p.23-30 |
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description | An extensive outbreak of influenza caused by A/USSR/77 (H1N1) virus occurred in February, 1978, at the University of Maryland, College Park, Maryland, and the outbreak was studied by virus isolation, serology, clinical questionnaire and outpatient chart review. Among students who returned questionnaires, clinical attack rates were extraordinarily high (73.2% of those ≤23 years of age and 45.7% for those >23 years (p < 0.001)), and rates were higher in students who lived on campus (p < 0.05). Employing the criterion of hemagglutination inhibition titer ≥16, 89.8% of those ≤23 years of age had evidence of infection by March, 1978. Illness was generally mild, and no complications were reported. The extent and rapid spread of this outbreak suggested that only immunoprophyiaxis or rapidly acting control measures such as chemoprophylaxis would be effective in this institutional setting with a highly susceptibie population. |
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Among students who returned questionnaires, clinical attack rates were extraordinarily high (73.2% of those ≤23 years of age and 45.7% for those >23 years (p < 0.001)), and rates were higher in students who lived on campus (p < 0.05). Employing the criterion of hemagglutination inhibition titer ≥16, 89.8% of those ≤23 years of age had evidence of infection by March, 1978. Illness was generally mild, and no complications were reported. 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Among students who returned questionnaires, clinical attack rates were extraordinarily high (73.2% of those ≤23 years of age and 45.7% for those >23 years (p < 0.001)), and rates were higher in students who lived on campus (p < 0.05). Employing the criterion of hemagglutination inhibition titer ≥16, 89.8% of those ≤23 years of age had evidence of infection by March, 1978. Illness was generally mild, and no complications were reported. The extent and rapid spread of this outbreak suggested that only immunoprophyiaxis or rapidly acting control measures such as chemoprophylaxis would be effective in this institutional setting with a highly susceptibie population.</description><subject>Adolescent</subject><subject>Adult</subject><subject>disease outbreaks</subject><subject>Disease Outbreaks - epidemiology</subject><subject>Humans</subject><subject>influenza</subject><subject>Influenza A virus</subject><subject>Influenza A Virus, H1N1 Subtype</subject><subject>Influenza, Human - diagnosis</subject><subject>Influenza, Human - epidemiology</subject><subject>Influenza, Human - etiology</subject><subject>Maryland</subject><subject>Middle Aged</subject><subject>Universities</subject><issn>0002-9262</issn><issn>1476-6256</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1980</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>K30</sourceid><recordid>eNpdkF9L40AUxQdRtHb3IwhBQfQh7b3zN-NbKNVWunGxRtSXYZLMQGtrNNOCfvvN0lrYfbn34Zxzz-VHyClCD0Gzfv3p66aa1-vmzS5Cz85dzyLSROEe6SBXMpZUyH3SAQAaayrpETkOYQ6AqAUckkPFBOVCdQiOs-tJPsxe0ijt59PpfV-p6GKEGV5Gd1mURnk2fhzeT8cPz9Eg_fU7n_4gB75tdT-3u0vy6-HDYBRP7m7Gg3QSlyyBVTsBGQglqRIJs54VSjL0VrFSuALBU8cTnhS-BKiYLWTpNS0rnSCrKGeedcn55u57U3-sXViZ5SyUbrGwb65eB6O41lxq3RrP_jN-kzHtB1IKjgJa19XGVTZ1CI3z5r2ZLW3zZRDMX6rmX6qmpWq2VNvwybZiXSxdtYtuMbZ6vNFnYeU-d7JtXo1UTAkzenox_PaJgUrAJOwPZGiBVw</recordid><startdate>198001</startdate><enddate>198001</enddate><creator>PONS, VINCENT G.</creator><creator>CANTER, JANE</creator><creator>DOLIN, RAPHAEL</creator><general>Oxford University Press</general><general>School of Hygiene and Public Health of the Johns Hopkins University</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>HVZBN</scope><scope>K30</scope><scope>PAAUG</scope><scope>PAWHS</scope><scope>PAWZZ</scope><scope>PAXOH</scope><scope>PBHAV</scope><scope>PBQSW</scope><scope>PBYQZ</scope><scope>PCIWU</scope><scope>PCMID</scope><scope>PCZJX</scope><scope>PDGRG</scope><scope>PDWWI</scope><scope>PETMR</scope><scope>PFVGT</scope><scope>PGXDX</scope><scope>PIHIL</scope><scope>PISVA</scope><scope>PJCTQ</scope><scope>PJTMS</scope><scope>PLCHJ</scope><scope>PMHAD</scope><scope>PNQDJ</scope><scope>POUND</scope><scope>PPLAD</scope><scope>PQAPC</scope><scope>PQCAN</scope><scope>PQCMW</scope><scope>PQEME</scope><scope>PQHKH</scope><scope>PQMID</scope><scope>PQNCT</scope><scope>PQNET</scope><scope>PQSCT</scope><scope>PQSET</scope><scope>PSVJG</scope><scope>PVMQY</scope><scope>PZGFC</scope><scope>7X8</scope></search><sort><creationdate>198001</creationdate><title>INFLUENZA A/USSR/77 (H1N1) ON A UNIVERSITY CAMPUS</title><author>PONS, VINCENT G. ; CANTER, JANE ; DOLIN, RAPHAEL</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c380t-c3013057627583af3b7631fa73c5eb10f2e4848bfc00d3ab6cf92cd9813d243f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1980</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>disease outbreaks</topic><topic>Disease Outbreaks - 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Among students who returned questionnaires, clinical attack rates were extraordinarily high (73.2% of those ≤23 years of age and 45.7% for those >23 years (p < 0.001)), and rates were higher in students who lived on campus (p < 0.05). Employing the criterion of hemagglutination inhibition titer ≥16, 89.8% of those ≤23 years of age had evidence of infection by March, 1978. Illness was generally mild, and no complications were reported. The extent and rapid spread of this outbreak suggested that only immunoprophyiaxis or rapidly acting control measures such as chemoprophylaxis would be effective in this institutional setting with a highly susceptibie population.</abstract><cop>United States</cop><pub>Oxford University Press</pub><pmid>7352457</pmid><doi>10.1093/oxfordjournals.aje.a112871</doi><tpages>8</tpages></addata></record> |
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subjects | Adolescent Adult disease outbreaks Disease Outbreaks - epidemiology Humans influenza Influenza A virus Influenza A Virus, H1N1 Subtype Influenza, Human - diagnosis Influenza, Human - epidemiology Influenza, Human - etiology Maryland Middle Aged Universities |
title | INFLUENZA A/USSR/77 (H1N1) ON A UNIVERSITY CAMPUS |
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