Metabolic Relationship Between Acetoacetate and Glucose
Summary 1. A metabolic relationship between glucose and acetoacetate has been shown to exist in the living body. 2. Increased concentration of acetoacetate (Na salt) distinctly inhibits normal glucose utilization when incubated at 37 ° C at a pH of 7.3 in the presence of whole blood (rabbit). 3. The...
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| Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1952-04, Vol.79 (4), p.608-610 |
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| container_end_page | 610 |
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| container_issue | 4 |
| container_start_page | 608 |
| container_title | Experimental biology and medicine (Maywood, N.J.) |
| container_volume | 79 |
| creator | Nath, Madhab Chandra Sahu, Virendra Kumar |
| description | Summary
1. A metabolic relationship between glucose and acetoacetate has been shown to exist in the living body. 2. Increased concentration of acetoacetate (Na salt) distinctly inhibits normal glucose utilization when incubated at 37 ° C at a pH of 7.3 in the presence of whole blood (rabbit). 3. The condensation product of glucose and ethylacetoacetate has no effect on the normal ketonemic level and blood sugar tolerance curve of a rabbit and has neither any abnormal effect on the urine constituents of the treated animals. |
| doi_str_mv | 10.3181/00379727-79-19462 |
| format | Article |
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1. A metabolic relationship between glucose and acetoacetate has been shown to exist in the living body. 2. Increased concentration of acetoacetate (Na salt) distinctly inhibits normal glucose utilization when incubated at 37 ° C at a pH of 7.3 in the presence of whole blood (rabbit). 3. The condensation product of glucose and ethylacetoacetate has no effect on the normal ketonemic level and blood sugar tolerance curve of a rabbit and has neither any abnormal effect on the urine constituents of the treated animals.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-79-19462</identifier><identifier>PMID: 14920511</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Acetoacetates - pharmacology ; Carbohydrate Metabolism ; Glucose - metabolism ; Old Medline</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1952-04, Vol.79 (4), p.608-610</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c338t-841e676ea5b8179c21acfc61436f9b4957f1decdc3b1a662a27b4ef67e30cebb3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27911,27912</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14920511$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nath, Madhab Chandra</creatorcontrib><creatorcontrib>Sahu, Virendra Kumar</creatorcontrib><title>Metabolic Relationship Between Acetoacetate and Glucose</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Summary
1. A metabolic relationship between glucose and acetoacetate has been shown to exist in the living body. 2. Increased concentration of acetoacetate (Na salt) distinctly inhibits normal glucose utilization when incubated at 37 ° C at a pH of 7.3 in the presence of whole blood (rabbit). 3. The condensation product of glucose and ethylacetoacetate has no effect on the normal ketonemic level and blood sugar tolerance curve of a rabbit and has neither any abnormal effect on the urine constituents of the treated animals.</description><subject>Acetoacetates - pharmacology</subject><subject>Carbohydrate Metabolism</subject><subject>Glucose - metabolism</subject><subject>Old Medline</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1952</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kLFOwzAQhi0EoqXwACwoE1uKL3bseCxVKUhFSAhmy3YukCqNS-wI8faktIiN5W647_-l-wi5BDplUMANpUwqmclUqhQUF9kRGUPO8pQJpY7JeHdPd8CInIWwphRymYlTMgKuMpoDjIl8xGisb2qXPGNjYu3b8F5vk1uMn4htMnMYvRmGiZiYtkyWTe98wHNyUpkm4MVhT8jr3eJlfp-unpYP89kqdYwVMS04oJACTW4LkMplYFzlBHAmKmW5ymUFJbrSMQtGiMxk0nKshERGHVrLJuR637vt_EePIepNHRw2jWnR90FLrobHORtA2IOu8yF0WOltV29M96WB6p0t_WtLS6V_bA2Zq0N5bzdY_iUOegZgugeCeUO99n3XDs_-0_gNC4VyVg</recordid><startdate>195204</startdate><enddate>195204</enddate><creator>Nath, Madhab Chandra</creator><creator>Sahu, Virendra Kumar</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>195204</creationdate><title>Metabolic Relationship Between Acetoacetate and Glucose</title><author>Nath, Madhab Chandra ; Sahu, Virendra Kumar</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c338t-841e676ea5b8179c21acfc61436f9b4957f1decdc3b1a662a27b4ef67e30cebb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1952</creationdate><topic>Acetoacetates - pharmacology</topic><topic>Carbohydrate Metabolism</topic><topic>Glucose - metabolism</topic><topic>Old Medline</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nath, Madhab Chandra</creatorcontrib><creatorcontrib>Sahu, Virendra Kumar</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nath, Madhab Chandra</au><au>Sahu, Virendra Kumar</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Metabolic Relationship Between Acetoacetate and Glucose</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1952-04</date><risdate>1952</risdate><volume>79</volume><issue>4</issue><spage>608</spage><epage>610</epage><pages>608-610</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Summary
1. A metabolic relationship between glucose and acetoacetate has been shown to exist in the living body. 2. Increased concentration of acetoacetate (Na salt) distinctly inhibits normal glucose utilization when incubated at 37 ° C at a pH of 7.3 in the presence of whole blood (rabbit). 3. The condensation product of glucose and ethylacetoacetate has no effect on the normal ketonemic level and blood sugar tolerance curve of a rabbit and has neither any abnormal effect on the urine constituents of the treated animals.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>14920511</pmid><doi>10.3181/00379727-79-19462</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0037-9727 |
| ispartof | Experimental biology and medicine (Maywood, N.J.), 1952-04, Vol.79 (4), p.608-610 |
| issn | 0037-9727 1535-3702 1535-3699 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_74994643 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Acetoacetates - pharmacology Carbohydrate Metabolism Glucose - metabolism Old Medline |
| title | Metabolic Relationship Between Acetoacetate and Glucose |
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