MB Creatine Kinase and the Evaluation of Myocardial Injury Following Aortocoronary Bypass Operation
Myocardial injury was studied in 104 patients undergoing coronary artery grafting without cold chemical cardioplegia using the quantity of the isoenzyme MB of the creatine kinase liberated as an indicator. This method of evaluation, which is said to permit comparison of different techniques of myoca...
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Veröffentlicht in: | The Annals of thoracic surgery 1980-01, Vol.29 (1), p.8-14 |
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container_title | The Annals of thoracic surgery |
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creator | du Cailar, Claude Maillé, Jean-Guy Jones, William Solymoss, B. Charles Chabot, Michel Goulet, Claude Delva, Eric Grondin, Claude M. |
description | Myocardial injury was studied in 104 patients undergoing coronary artery grafting without cold chemical cardioplegia using the quantity of the isoenzyme MB of the creatine kinase liberated as an indicator. This method of evaluation, which is said to permit comparison of different techniques of myocardial protection, allowed us to consider the relative importance of several factors believed to have an influence on intraoperative myocardial injury. Indices of significance were duration of symptoms before operation, presence of chronic arterial hypertension, and the type of antiangina treatment employed. Other operative factors included severity of the arterial lesions, number of anastomoses performed, and duration of extracorporeal circulation and of aortic cross-clamping. |
doi_str_mv | 10.1016/S0003-4975(10)61618-9 |
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Charles ; Chabot, Michel ; Goulet, Claude ; Delva, Eric ; Grondin, Claude M.</creator><creatorcontrib>du Cailar, Claude ; Maillé, Jean-Guy ; Jones, William ; Solymoss, B. Charles ; Chabot, Michel ; Goulet, Claude ; Delva, Eric ; Grondin, Claude M.</creatorcontrib><description>Myocardial injury was studied in 104 patients undergoing coronary artery grafting without cold chemical cardioplegia using the quantity of the isoenzyme MB of the creatine kinase liberated as an indicator. This method of evaluation, which is said to permit comparison of different techniques of myocardial protection, allowed us to consider the relative importance of several factors believed to have an influence on intraoperative myocardial injury. Indices of significance were duration of symptoms before operation, presence of chronic arterial hypertension, and the type of antiangina treatment employed. Other operative factors included severity of the arterial lesions, number of anastomoses performed, and duration of extracorporeal circulation and of aortic cross-clamping.</description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/S0003-4975(10)61618-9</identifier><identifier>PMID: 6965445</identifier><language>eng</language><publisher>Netherlands: Elsevier Inc</publisher><subject>Angina Pectoris - complications ; Angina Pectoris - drug therapy ; Angina Pectoris - pathology ; Coronary Artery Bypass - methods ; Coronary Vessels - pathology ; Creatine Kinase - blood ; Extracorporeal Circulation ; Female ; Humans ; Hypertension - complications ; Isoenzymes ; Male ; Middle Aged ; Myocardial Infarction - enzymology ; Myocardial Infarction - pathology ; Myocardial Infarction - surgery ; Myocardium - pathology ; Propranolol - therapeutic use</subject><ispartof>The Annals of thoracic surgery, 1980-01, Vol.29 (1), p.8-14</ispartof><rights>1980 The Society of Thoracic Surgeons</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c440t-723bf9be457a3ff781cc9e596fdb4a71af68a5298c072d880a584d9b6159dd393</citedby><cites>FETCH-LOGICAL-c440t-723bf9be457a3ff781cc9e596fdb4a71af68a5298c072d880a584d9b6159dd393</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6965445$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>du Cailar, Claude</creatorcontrib><creatorcontrib>Maillé, Jean-Guy</creatorcontrib><creatorcontrib>Jones, William</creatorcontrib><creatorcontrib>Solymoss, B. Charles</creatorcontrib><creatorcontrib>Chabot, Michel</creatorcontrib><creatorcontrib>Goulet, Claude</creatorcontrib><creatorcontrib>Delva, Eric</creatorcontrib><creatorcontrib>Grondin, Claude M.</creatorcontrib><title>MB Creatine Kinase and the Evaluation of Myocardial Injury Following Aortocoronary Bypass Operation</title><title>The Annals of thoracic surgery</title><addtitle>Ann Thorac Surg</addtitle><description>Myocardial injury was studied in 104 patients undergoing coronary artery grafting without cold chemical cardioplegia using the quantity of the isoenzyme MB of the creatine kinase liberated as an indicator. This method of evaluation, which is said to permit comparison of different techniques of myocardial protection, allowed us to consider the relative importance of several factors believed to have an influence on intraoperative myocardial injury. Indices of significance were duration of symptoms before operation, presence of chronic arterial hypertension, and the type of antiangina treatment employed. Other operative factors included severity of the arterial lesions, number of anastomoses performed, and duration of extracorporeal circulation and of aortic cross-clamping.</description><subject>Angina Pectoris - complications</subject><subject>Angina Pectoris - drug therapy</subject><subject>Angina Pectoris - pathology</subject><subject>Coronary Artery Bypass - methods</subject><subject>Coronary Vessels - pathology</subject><subject>Creatine Kinase - blood</subject><subject>Extracorporeal Circulation</subject><subject>Female</subject><subject>Humans</subject><subject>Hypertension - complications</subject><subject>Isoenzymes</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Myocardial Infarction - enzymology</subject><subject>Myocardial Infarction - pathology</subject><subject>Myocardial Infarction - surgery</subject><subject>Myocardium - pathology</subject><subject>Propranolol - therapeutic use</subject><issn>0003-4975</issn><issn>1552-6259</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1980</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1PxCAQhonR6PrxE0w4GT1UoQVaTsbd-BU1HtQzoTBVTBdWaDX77213N149TZj3nXmHB6FjSs4poeLihRBSZEyW_JSSM0EFrTK5hSaU8zwTOZfbaPJn2UP7KX0Oz3yQd9GukIIzxifIPE3xLILunAf84LxOgLW3uPsAfP2t235QgsehwU_LYHS0Trf43n_2cYlvQtuGH-ff8VWIXTAhBq-H_nS50Cnh5wXE1fQh2ml0m-BoUw_Q28316-wue3y-vZ9dPWaGMdJlZV7UjayB8VIXTVNW1BgJXIrG1kyXVDei0jyXlSFlbquKaF4xK2tBubS2kMUBOlnvXcTw1UPq1NwlA22rPYQ-qXIkwWg-GPnaaGJIKUKjFtHNh9MVJWqEq1Zw1egfWyu4agw43gT09Rzs39SG5qBfrnUYfvntIKpkHHgD1kUwnbLB_ZPwC0QFigw</recordid><startdate>19800101</startdate><enddate>19800101</enddate><creator>du Cailar, Claude</creator><creator>Maillé, Jean-Guy</creator><creator>Jones, William</creator><creator>Solymoss, B. 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Charles ; Chabot, Michel ; Goulet, Claude ; Delva, Eric ; Grondin, Claude M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c440t-723bf9be457a3ff781cc9e596fdb4a71af68a5298c072d880a584d9b6159dd393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1980</creationdate><topic>Angina Pectoris - complications</topic><topic>Angina Pectoris - drug therapy</topic><topic>Angina Pectoris - pathology</topic><topic>Coronary Artery Bypass - methods</topic><topic>Coronary Vessels - pathology</topic><topic>Creatine Kinase - blood</topic><topic>Extracorporeal Circulation</topic><topic>Female</topic><topic>Humans</topic><topic>Hypertension - complications</topic><topic>Isoenzymes</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Myocardial Infarction - enzymology</topic><topic>Myocardial Infarction - pathology</topic><topic>Myocardial Infarction - surgery</topic><topic>Myocardium - pathology</topic><topic>Propranolol - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>du Cailar, Claude</creatorcontrib><creatorcontrib>Maillé, Jean-Guy</creatorcontrib><creatorcontrib>Jones, William</creatorcontrib><creatorcontrib>Solymoss, B. 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Charles</au><au>Chabot, Michel</au><au>Goulet, Claude</au><au>Delva, Eric</au><au>Grondin, Claude M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>MB Creatine Kinase and the Evaluation of Myocardial Injury Following Aortocoronary Bypass Operation</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>1980-01-01</date><risdate>1980</risdate><volume>29</volume><issue>1</issue><spage>8</spage><epage>14</epage><pages>8-14</pages><issn>0003-4975</issn><eissn>1552-6259</eissn><abstract>Myocardial injury was studied in 104 patients undergoing coronary artery grafting without cold chemical cardioplegia using the quantity of the isoenzyme MB of the creatine kinase liberated as an indicator. This method of evaluation, which is said to permit comparison of different techniques of myocardial protection, allowed us to consider the relative importance of several factors believed to have an influence on intraoperative myocardial injury. Indices of significance were duration of symptoms before operation, presence of chronic arterial hypertension, and the type of antiangina treatment employed. Other operative factors included severity of the arterial lesions, number of anastomoses performed, and duration of extracorporeal circulation and of aortic cross-clamping.</abstract><cop>Netherlands</cop><pub>Elsevier Inc</pub><pmid>6965445</pmid><doi>10.1016/S0003-4975(10)61618-9</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Angina Pectoris - complications Angina Pectoris - drug therapy Angina Pectoris - pathology Coronary Artery Bypass - methods Coronary Vessels - pathology Creatine Kinase - blood Extracorporeal Circulation Female Humans Hypertension - complications Isoenzymes Male Middle Aged Myocardial Infarction - enzymology Myocardial Infarction - pathology Myocardial Infarction - surgery Myocardium - pathology Propranolol - therapeutic use |
title | MB Creatine Kinase and the Evaluation of Myocardial Injury Following Aortocoronary Bypass Operation |
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