Experimental ocular cryptococcosis. Preliminary studies in cats and mice
Ocular cryptococcosis was produced in cats by the intracarotid injection of Cryptococcus neoformans. Infected eyes developed a progressive, multifocal chorioretinitis which was comparable to that found in the naturally occurring feline disease. The severity of the ocular disease, the development of...
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| Veröffentlicht in: | Investigative ophthalmology & visual science 1980-01, Vol.19 (1), p.21-30 |
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| creator | Blouin, P Cello, R M |
| description | Ocular cryptococcosis was produced in cats by the intracarotid injection of Cryptococcus neoformans. Infected eyes developed a progressive, multifocal chorioretinitis which was comparable to that found in the naturally occurring feline disease. The severity of the ocular disease, the development of infection in the fellow eye, and the degree of systemic involvement were shown to be related to the number of organisms inoculated. Mice infected intracerebrally with the same organism developed optic nerve meningitis. The pathogenesis of the ocular lesions thus produced is discussed. |
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The pathogenesis of the ocular lesions thus produced is discussed.</description><identifier>ISSN: 0146-0404</identifier><identifier>PMID: 7350131</identifier><language>eng</language><publisher>United States</publisher><subject>Animals ; Cats ; Chorioretinitis - microbiology ; Chorioretinitis - pathology ; Cryptococcosis - microbiology ; Cryptococcosis - mortality ; Cryptococcosis - pathology ; Cryptococcus - isolation & purification ; Cryptococcus - pathogenicity ; Dogs ; Mice ; Optic Nerve Diseases - microbiology ; Optic Nerve Diseases - pathology</subject><ispartof>Investigative ophthalmology & visual science, 1980-01, Vol.19 (1), p.21-30</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7350131$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Blouin, P</creatorcontrib><creatorcontrib>Cello, R M</creatorcontrib><title>Experimental ocular cryptococcosis. Preliminary studies in cats and mice</title><title>Investigative ophthalmology & visual science</title><addtitle>Invest Ophthalmol Vis Sci</addtitle><description>Ocular cryptococcosis was produced in cats by the intracarotid injection of Cryptococcus neoformans. Infected eyes developed a progressive, multifocal chorioretinitis which was comparable to that found in the naturally occurring feline disease. The severity of the ocular disease, the development of infection in the fellow eye, and the degree of systemic involvement were shown to be related to the number of organisms inoculated. Mice infected intracerebrally with the same organism developed optic nerve meningitis. The pathogenesis of the ocular lesions thus produced is discussed.</description><subject>Animals</subject><subject>Cats</subject><subject>Chorioretinitis - microbiology</subject><subject>Chorioretinitis - pathology</subject><subject>Cryptococcosis - microbiology</subject><subject>Cryptococcosis - mortality</subject><subject>Cryptococcosis - pathology</subject><subject>Cryptococcus - isolation & purification</subject><subject>Cryptococcus - pathogenicity</subject><subject>Dogs</subject><subject>Mice</subject><subject>Optic Nerve Diseases - microbiology</subject><subject>Optic Nerve Diseases - pathology</subject><issn>0146-0404</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1980</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNotj8FKxDAURbNQxnH0E4Ss3FWSl6RplzKMjjCgC12X9CWBSNvUJAXn7y04q7s5XM65IlvGZV0xyeQNuc35mzHgHNiGbLRQjAu-JcfD7-xSGN1UzEAjLoNJFNN5LhEjYswhP9GP5IYwhsmkM81lscFlGiaKpmRqJkvHgO6OXHszZHd_2R35ejl87o_V6f31bf98qmZgdakAwHNutepF49EaDkpAz7Vv0TDupa6lB9s0oGutZAuu9w2zyqFXhuHqvCOP_79zij-Ly6UbQ0Y3DGZyccmdlm0tGMgVfLiASz86281r5RrQXdLFH0_yVCk</recordid><startdate>198001</startdate><enddate>198001</enddate><creator>Blouin, P</creator><creator>Cello, R M</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>198001</creationdate><title>Experimental ocular cryptococcosis. Preliminary studies in cats and mice</title><author>Blouin, P ; Cello, R M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p206t-222f11d75b38fcda12532b17f9ca01f4764f2d8827675492ebf80d5ecf5a0c013</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1980</creationdate><topic>Animals</topic><topic>Cats</topic><topic>Chorioretinitis - microbiology</topic><topic>Chorioretinitis - pathology</topic><topic>Cryptococcosis - microbiology</topic><topic>Cryptococcosis - mortality</topic><topic>Cryptococcosis - pathology</topic><topic>Cryptococcus - isolation & purification</topic><topic>Cryptococcus - pathogenicity</topic><topic>Dogs</topic><topic>Mice</topic><topic>Optic Nerve Diseases - microbiology</topic><topic>Optic Nerve Diseases - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Blouin, P</creatorcontrib><creatorcontrib>Cello, R M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Investigative ophthalmology & visual science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Blouin, P</au><au>Cello, R M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Experimental ocular cryptococcosis. Preliminary studies in cats and mice</atitle><jtitle>Investigative ophthalmology & visual science</jtitle><addtitle>Invest Ophthalmol Vis Sci</addtitle><date>1980-01</date><risdate>1980</risdate><volume>19</volume><issue>1</issue><spage>21</spage><epage>30</epage><pages>21-30</pages><issn>0146-0404</issn><abstract>Ocular cryptococcosis was produced in cats by the intracarotid injection of Cryptococcus neoformans. Infected eyes developed a progressive, multifocal chorioretinitis which was comparable to that found in the naturally occurring feline disease. The severity of the ocular disease, the development of infection in the fellow eye, and the degree of systemic involvement were shown to be related to the number of organisms inoculated. Mice infected intracerebrally with the same organism developed optic nerve meningitis. The pathogenesis of the ocular lesions thus produced is discussed.</abstract><cop>United States</cop><pmid>7350131</pmid><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0146-0404 |
| ispartof | Investigative ophthalmology & visual science, 1980-01, Vol.19 (1), p.21-30 |
| issn | 0146-0404 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_74963024 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Animals Cats Chorioretinitis - microbiology Chorioretinitis - pathology Cryptococcosis - microbiology Cryptococcosis - mortality Cryptococcosis - pathology Cryptococcus - isolation & purification Cryptococcus - pathogenicity Dogs Mice Optic Nerve Diseases - microbiology Optic Nerve Diseases - pathology |
| title | Experimental ocular cryptococcosis. Preliminary studies in cats and mice |
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